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Table 3 G6PD activity and reticulocyte count in the G6PD deficiency, intermediate, and normal newborn groups

From: Effect of neonatal reticulocytosis on glucose 6-phosphate dehydrogenase (G6PD) activity and G6PD deficiency detection: a cross-sectional study

Parameter

G6PD Normal

G6PD Intermediate

G6PD Deficiency

Total

Male

Female

Total

Male

Female

Total

Male

Female

Spectrophotometric assay (n)

837

423

414

116

29

87

62

50

12

G6PD activity (U/g Hb)

10.48 ± 2.18

10.52 ± 2.15

10.45 ± 2.23

6.34 ± 2.40

7.63 ± 1.01

6.04 ± 1.92

1.33 ± 0.75

1.21 ± 0.76

1.56 ± 1.67

Reticulocyte count (%)

4.78 ± 1.29

4.56 ± 1.20

5.01 ± 1.33

5.03 ± 1.43

4.31 ± 1.69

5.27 ± 1.25

5.82 ± 1.73a

5.86 ± 1.90b

5.65 ± 0.69c

Automated UV enzymatic assay (n)

791

403

388

158

47

111

66

52

14

G6PD activity (U/g Hb)

27.45 ± 6.63

27.26 ± 6.68

27.50 ± 6.63

16.49 ± 6.37

18.26 ± 2.81

14.75 ± 6.22

1.81 ± 0.90

1.76 ± 0.70

2.11 ± 5.44

Reticulocyte count (%)

4.82 ± 1.29

4.60 ± 1.20

5.04 ± 1.34

4.76 ± 1.37

3.94 ± 1.25b

5.10 ± 1.28

5.83 ± 1.71a

5.91 ± 1.88b

5.52 ± 0.75c

  1. Values are expressed as the mean ± SD
  2. a compared to the normal group (p < 0.001) (t-test)
  3. b compared to males in the normal group (p < 0.001) (t-test)
  4. c compared to females in the normal group (p < 0.05) (t-test)