Table 2 Comparison of mean ± SD and frequency distribution of Patient’s laboratory findings and dietary intake of PKU patients

Age (y)

9.01 ± 3.64

9.81 ± 4.11

7.97 ± 2.65

0.043

Gender (female)

42 (52.5%)

23 (51.1%)

19 (54.3%)

0.778^b

Time of diagnosis (≤ 2week)

68 (85%)

36 (80%)

32 (91.4)

0.156^b

Phenotype (classic)

64 (80%)

36 (80%)

28 (80%)

1

Consanguineous marriage

46 (57.5%)

23 (51.1%)

23 (65.7%)

0.13

Dietary intake

Energy (kcal)

1323.29 ± 392.79

1373.85 ± 435.07

1258.28 ± 325.25

0.197

Protein (g)

51.95 ± 16.03

53.22 ± 16.54

50.31 ± 15.43

0.423

Fat (g)

41.02 ± 25.25

42.43 ± 29.30

39.22 ± 19.09

0.734^a

Carbohydrate (g)

193.85 ± 63.97

200.56 ± 66.97

185.21 ± 59.73

0.260

Phe intake (mg)

655.86 ± 663.08

758,94 ± 785.45

523.33 ± 437.10

0.120

Laboratory data

Plasma Phe level (mg/dl)

11.26 ± 7.16

12.17 ± 8.20

10.09 ± 5.43

0.446^a

Plasma Tyr level (mg/dl)

1.20 ± 0.69

1.21 ± 0.77

1.18 ± 0.58

0.662^a

Serum albumin level (g/dl)

4.39 ± 0.27

4,40 ± 0.28

4.37 ± 0.27

0.591^a

Serum iron level (µg/dl)

85.31 ± 34.39

95.15 ± 36.42

72.65 ± 27.18^b

0.003

Serum calcium level (mg/dl)

10.18 ± 0.40

10.16 ± 0.42

10.20 ± 0.39

0.667

Serum zinc level (µg/dl)

95.35 ± 28.53

96.33 ± 27.72

94.08 ± 29.91

0.729

Serum folic acid (ng/ml)

18.75 ± 12.59

17.02 ± 9.28

20.97 ± 15.74

0.229^a

Serum vitamin B12 level (pg/ml)

806.03 ± 426.12

741.82 ± 397.30

888.59 ± 452.94

0.127^a

Serum ferritin level (ng/ml)

43.82 ± 49.51

39.01 ± 19.71

49.99 ± 71.58

0.617^a

Serum 25-Hydroxy vitamin D3 level (ng/ml)

37.28 ± 20.19

37.07 ± 22.47

37.55 ± 17.12

0.713