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Fig. 1 | BMC Pediatrics

Fig. 1

From: Early molecular diagnosis of BRAF status drives the neurosurgical management in BRAF V600E-mutant pediatric low-grade gliomas: a case report

Fig. 1

Brain MRI of the 12-year-old girl with ganglioglioma. T2-weighted axial sequences at baseline (after biopsy) show a heterogeneous mass with epicenter in the hypothalamic-chiasmatic region, prominent involvement of the left basal ganglia and thalamus, and caudal exophytic extension with midbrain compression. Follow-up MRI at 1 month from starting vemurafenib shows quick and evident shrinkage (-45%, according to RANO criteria) with prominent regression of the left prepontine component. Mass reduction continues at 5 months (-70%) and is stable at 12 months (-76%)

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BMC Pediatrics

ISSN: 1471-2431

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