Variables |  | cOR, 95% CI | P-value | aOR, 95% CI Model 1†| P-value | aOR, 95% CI Model 2¥ | P-value | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Caregiver’s substance use | No | Ref. |  | Ref. |  | Ref. |  | |||||||
Yes | 2.92 (1.70, 5.02) | < 0.001 | 2. 47 (1.31, 4.66) | 0.005 | 2.87 (1.44, 5.71) | 0.003 | ||||||||
Child age | 6–9 | Ref. |  | Ref. |  | Ref. |  | |||||||
10–14 years | 0.28 (0.13, 0.60) | 0.001 | 0. 62 (0.25, 1.51) | 0.290 | 0.34 (0.12, 0.99) | 0.048 | ||||||||
15–17 years | 0.21 (0.10, 0.45) | < 0.001 | 1.44 (0.42, 4.91) | 0.557 | 0.83 (0.21, 3.33) | 0.789 | ||||||||
HIV status disclosure | No | Ref. | Â | Ref. | Â | Ref. | Â | |||||||
Yes | 0.22 (0.12, 0.38) | < 0.001 | 0.31 (0.14, 0.69) | 0.004 | 0.30 (0.13, 0.72) | 0.007 | ||||||||
ART dose | Once daily | Ref. | < 0.001 | Ref. |  | Ref. |  | |||||||
12 hourly (two doses) | 2.66 (1.55, 4.58) | Â | 0.50 (0.19, 1.34) | 0.168 | 0.41 (0.15, 1.14) | 0.086 | ||||||||
Monthly family income (in ETB) | <2500 | Ref. | Â | Ref. | Â | Ref. | Â | |||||||
 | 2500–4999 | 1.23 (0.71, 2.15) | 0.464 | 1.43 (0.75, 2.72) | 0.279 | 1.65 (0.82, 3.35) | 0.164 | |||||||
 | ≥ 5000 | 0.77 (0.27, 2.22) | 0.633 | 0.73 (0.22, 2.38) | 0.598 | 0.76 (0.22, 2.66) | 0.669 | |||||||
Relation with child | Biological parent | Ref. | Â | Ref. | Â | Ref. | Â | |||||||
 | Non-biological parent | 0.98 (0.48, 1.97) | 0.945 | 1.52 (0.56, 4.11) | 0.410 | 1.76 (0.59, 5.25) | 0.314 | |||||||
Caregiver’s HIV status | Positive | Ref. |  | Ref. |  | Ref. |  | |||||||
Negative | 0.64 (0.26, 1.54) | 0.315 | 0.55 (0.16, 1.85) | 0.334 | 0.65 (0.17, 2.52) | 0.531 | ||||||||
ART regimen backbone | TDF + 3TC | Ref. |  | Ref. |  | Ref. |  | |||||||
AZT + 3TC | 5.44 (2.87, 10.30) | < 0.001 | 5.40 (1.95, 14.98) | 0.001 | 4.12 (1.43, 11.86) | 0.009 | ||||||||
ABC + 3TC | 4.31 (2.06, 9.01) | < 0.001 | 5.56 (1.85, 16.73) | 0.002 | 5.58 (1.70, 18.30) | 0.005 | ||||||||
Viral load change against the first measurement | Remained ND | Ref. | Â | *** | *** | Ref. | Â | |||||||
Decreased to or remained < 1000 | 3.47 (1.41, 8.51) | 0.007 | *** | *** | 4.87 (1.65, 14.33) | 0.004 | ||||||||
Remained at > = 1000 or increased from ND | 6.90 (3.18, 14.98) | < 0.001 | *** | *** | 9.30 (3.69, 23.46) | < 0.001 |