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Table 3 Clinical, biochemical and radiological characteristics associated with antibodies state. TA, thyroid antibodies; ND, not done; TSH, thyroid Stimulating Hormone, FT: free thyroxin

From: Prevalence of thyroid nodules and characteristics of thyroid ultrasound in children with goiter: a single center experience

 

TA negative

(n = 55)

TA positive

(n = 119)

 

P- value

Gender (n, %)

   

0.018*

Male

13 (23.6)

12 (10.1)

 

Female

42 (76.4)

107 (89.9)

 

Mean TSH* (SD)

3.88 + 11.75

12.96 + 44.31

 

0.137

Mean FT4 (S)

13.59 + 3.79

13.49 + 5.12

 

0.904

Levothyroxine Usage (n, %)

   

< 0.001*

Yes

8 (14.5)

73 (61.3)

 

No

47 (85.5)

46 (38.7)

 

Presence of nodule (n, %)

Yes

No

Heterogenicity (n, %)

24 (43.6%)

31 (56.4%)

31 (26.5%)

86 (73.5%)

 

0.025*

< 0.001*

Homogenous

32 (62.7)

13 (11.2)

 

Heterogenous

19 (37.3)

103 (88.8)

 

Echogenicity (n, %)

   

0.427

Normal

53 (96.4)

111 (93.3)

 

Hypoechoic

1 (1.8)

7 (5.9)

 

Hyperechoic

1 (1.8)

1 (0.8)

 

Vascularity (n, %)

   

< 0.001*

Normal

23 (63.9)

11 (10.3)

 

Hyper-vascular

12 (33.3)

95 (88.8)

 

Hypo-vascular

1 (2.8)

1 (0.9)

 
  1. *TSH value represent the baseline level before starting levothyroxine
  2. +Significant at level 0.05.