Table 1 Bivariable and Multivariable Cox regression analysis of predictors of Death among HIV infected under five children receiving ART in West Amhara Referral Hospitals between January 2010 and December 2019

Age of the child

 < 12 months

3

28

2.40(0.71, 8.08)

2.17(0.47, 10.02)

12 -59 months

22

362

1

1

Age of caregiver

18–30 years

9

179

1

1

31–40 years

9

150

1.22(0.48, 3.08)

0.58(0.18, 1.82)

41–50 years

3

41

2.28(0.61, 8.56)

1.20(0.24, 6.05)

 > 50 years

4

20

7.88(2.35, 26.48)*

0.76(0.14, 4.19)

Status of parents

Both alive

17

304

1

1

mother alive but father dead

2

29

1.31(0.30, 5.67)

0.86(0.16, 4.63)

Mother dead, but father alive

3

13

4.16(1.2, 14.25)*

1.72(0.37, 8.13)

Both dead

3

44

2.34(0.68, 8.11)

0.75(0.16, 3.46)

Residence

Urban

11

274

1

1

Rural

14

116

3.85(1.73, 8.58)*

3.32(1.17, 9.39)

OI at baseline

Yes

22

239

4.52(1.35, 15.12)*

1.79(0.35, 9.11)

No

3

151

1

1

CD4 count or percent

Above the threshold

5

179

1

1

Below the threshold

20

211

2.28(0.91, 5.73)*

0.96(0.32, 2.91)

ART adherence status

Good

11

308

1

1

Fair

6

51

3.04 (1.12, 8.22)

1.88(0.53,6.7)

Poor

8

31

6.00(2.40, 15.01)*

3.36(1.06, 10.69)

CPT

Yes

20

352

1

1

No

5

38

4.50(1.66, 12.19)*

1.81(0.50,6.58)

IPT

Yes

6

192

1

1

No

19

198

4.67(1.86, 11.75)*

3.15(1.11, 8.94)

OI’s during follow up

Yes

19

159

2.79(1.11, 7.049)*

1.51(0.52, 4.34)*

No

6

231

1

1

Baseline hemoglobin(Hgb)

Anemic(< 10 g/dl)

12

39

7.40(3.37, 16.23)*

3.05 (1.16, 8.03)

Nonanemic(≥ 10 g/d)

13

351

1

1

Baseline WHO Clinical Stages

Mild (stage I & II)

5

218

1

1

Advanced (stage III&IV)

20

172

5.00(1.88, 13.36)*

1.15(0.27, 4.86)