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Table 6 Effects of different combinations of genetic polymorphisms (PART1 rs27565 and DEFB1 rs11362) and the frequency of sugary food intake on caries

From: Associations of PART1 and DEFB1 polymorphisms with Dental Caries in twelve-year-old children in Southern China: a cross-sectional study

SNP

Combination

Caries-free

n (%)

Caries experience

n (%)

OR

95% CI

P* value

PART1 rs27565

      
 

TT/sugary food intake ≤ once/week

77 (13.1)

43 (9.1)

Ref

  
 

TT/sugary food intake > once/week

112 (19.1)

75 (15.8)

1.054

0.649–1.711

0.832

 

TC + CC/sugary food intake ≤ once/week

140 (23.9)

89 (18.7)

1.084

0.682–1.723

0.734

 

TC + CC/sugary food intake > once/week

257 (43.9)

268 (56.4)

1.579

1.032–2.414

0.035

DEFB1 rs11362

      
 

CC/sugary food intake ≤ once/week

132 (22.5)

72 (15.2)

Ref

  
 

CC/sugary food intake > once/week

205 (35.0)

153 (32.2)

1.324

0.926–1.894

0.124

 

CT + TT/sugary food intake ≤ once/week

85 (14.5)

60 (12.6)

1.297

0.835–2.015

0.247

 

CT + TT/sugary food intake > once/week

164 (28.0)

190 (40.0)

2.057

1.438–2.940

< 0.001

  1. SNP: single-nucleotide polymorphism, OR: odds ratio, CI: confidence interval
  2. *: Adjusted for sex and ethnicity