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Table 2 Changes of eGFR and proteinuria of the total cohort during the first 6 months of follow-up. P values are shown for the difference between the values at month 3 (M3) and month 6 (M6) versus the values at onset

From: Early clinical course of biopsy-proven IgA vasculitis nephritis

 

Onset of disease

M1

M2

M3

p

M4

M5

M6

p

Median eGFR [ml/min/1.73m2]

86.7

101.1

101.4

98.0

0.214

103.6

105.0

101.6

0.190

eGFR < 90 ml/min/1.73m2 [%]

50.0

35.1

39.7

34.9

0.449

44.4

34.6

35.5

0.106

Median proteinuria [g/g creatinine]

3.7

1.7

1.2

0.7

 < 0,001

0.5

0.4

0.3

 < 0,001

Nephrotic-range proteinuria [%]

80.3

40.4

25.9

11.5

 < 0,001

6.3

9.8

7.0

 < 0,001

Non-nephrotic range proteinuria [%]

16.4

56.3

70.0

89.6

 < 0,001

93.5

89.8

92.5

 < 0,001

No proteinuria [%]

0

0

0

0

 

8.3

18.0

30.9

 < 0,001

Remission [%]

0

0

0

0

 

3.9

13.5

27.1

 < 0,001