Table 3 Comparison of NT-probNP, 25-(OH) D, HMGB1, ACTA, blood glucose level and electrolyte level in neonates with different severity of hypoxic-ischemic encephalopathy (mean±SD)

NT-ProBNP (pmol/L)

223.28±25.29

241.87±22.76^#

268.92±23.28^#*

10.405

<0.001

25-(OH) D (ng/ml)

26.87±2.22

22.09±2.19^#

16.37±2.07^#*

153.657

<0.001

HMGB1(μg/L)

6.27±1.68

8.97±1.72^#

10.93±1.67^#*

19.539

<0.001

ACTA (ng/ml)

17.82±0.93

23.27±0.91^#

27.98±0.97^#*

308.43

<0.001

Blood glucose (n,%)

10.067

0.007

 Hypoglycemia

22

17

16^#*

 Hyperglycemia

29

14

3^#*

Electrolyte

  K⁺(mmol/L)

4.56±0.14

4.41±0.23^#

4.27±0.18^#*

5.218

<0.001

  Na⁺(mmol/L)

125.33±12.09

119.83±12.34^#

103.29±12.18^#*

10.264

<0.001

  Ca²⁺(mmol/L)

2.07±0.21

1.73±0.19^#

1.48±0.17^#*

25.036

<0.001

  Mg²⁺(mmol/L)

0.76±0.10

0.63±0.09^#

0.51±0.12^#*

16.134

<0.001