Fig. 3
From: A novel variant in the ROR2 gene underlying brachydactyly type B: a case report
Gene variant analysis of a family with BDB1. a The novel heterozygous variant c.1320dupG, p.(Arg441Alafs*18) in ROR2 was verified by Sanger sequencing. The variant is marked by a red arrow. CS: Clone sequencing. b A schematic diagram showing the encoded domain structure of the ROR2 gene. A recurrent variant is marked in black, and the novel variant identified in this study is highlighted in red. This ROR2 variant results in the loss of the whole intracellular region