Outcome | Tight glycemic control (n = 124) | Standard care (n = 145) | pa |
---|---|---|---|
Bayley-III scoresb | (n = 96) | (n = 118) | |
Age at testing, mean ± SD, mo | 37.0 ± 2.7 | 37.1 ± 2.6 | 0.93 |
Composite scores, mean ± SD | |||
Cognitive | 94.6 ± 14.7 | 95.7 ± 13.2 | 0.66 |
Language | 97.8 ± 19.9 | 99.8 ± 17.2 | 0.44 |
Motor | 89.3 ± 17.4 | 92.6 ± 16.9 | 0.19 |
Subscale scores, mean ± SD | |||
Cognitive | 8.9 ± 2.9 | 9.1 ± 2.6 | 0.66 |
Receptive communication | 9.9 ± 3.4 | 10.2 ± 2.8 | 0.52 |
Expressive communication | 9.2 ± 3.6 | 9.6 ± 3.3 | 0.36 |
Fine motor | 8.9 ± 3.0 | 9.4 ± 3.0 | 0.27 |
Gross motor | 7.5 ± 3.1 | 8.1 ± 3.0 | 0.16 |
ABAS-II composite scores,mean ± SDc | (n = 84) | (n = 100) | |
General Adaptive Composite | 89.2 ± 21.6 | 91.7 ± 19.4 | 0.42 |
Conceptual | 95.0 ± 21.2 | 96.5 ± 19.5 | 0.64 |
Social | 91.6 ± 20.4 | 95.5 ± 17.3 | 0.17 |
Practical | 85.1 ± 19.8 | 87.3 ± 17.0 | 0.42 |
BASC-2 composite T-scores,mean ± SDd | (n = 93) | (n = 116) | |
Externalizing | 45.7 ± 9.7 | 46.8 ± 9.3 | 0.40 |
Internalizing | 47.5 ± 10.2 | 47.6 ± 9.3 | 0.99 |
Behavioral symptoms | 46.6 ± 9.4 | 46.7 ± 8.6 | 0.98 |
Adaptive skills | 48.9 ± 9.7 | 50.4 ± 9.5 | 0.27 |
ASQ-3, at risk,n (%)e | (n = 112) | (n = 131) | |
Communication | 25 (22) | 24 (18) | 0.52 |
Gross motor | 30 (27) | 30 (23) | 0.55 |
Fine motor | 23 (21) | 16 (12) | 0.11 |
Problem solving | 28 (25) | 24 (18) | 0.27 |
Personal-social | 30 (27) | 23 (18) | 0.09 |