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Table 1 The Characteristics of patients with Kawasaki disease according to IVIG responsiveness

From: A decision tree model for predicting intravenous immunoglobulin resistance and coronary artery involvement in Kawasaki disease

 

IVIG responders (N = 117)

IVIG non-responders (N = 785)

P value

Age, months

31.43 ± 22.44

36.39 ± 27.70

0.07

Sex

 Male, n (%)

444 (56.5%)

67 (60.3%)

0.47

 Female, n (%)

341 (43.4%)

44 (39.6%)

 

WBC, 103/L

14.8 ± 4.6

15.2 ± 6.0

0.36

ANC, 103/L

9.56 ± 4.4

11.36 ± 5.3

 < 0.01*

Hematocrit, %

34.3 ± 12.7

35.2 ± 5.7

0.43

Platelet, 103/L

361.46 ± 100.66

322.14 ± 105.44

 < 0.01*

AST, U/L

79.8 ± 138.8

135.6 ± 201.5

 < 0.01*

ALT, U/L

79.7 ± 127.9

159.1 ± 188.3

 < 0.01*

Albumin, g/dL

3.97 ± 0.9

3.80 ± 0.5

0.06

Total bilirubin, mg/dL

0.62 ± 0.8

1.38 ± 1.4

 < 0.01*

CRP, mg/dL

8.02 ± 5.9

9.92 ± 6.3

 < 0.01*

Na, mmol/L

136.3 ± 2.8

135.8 ± 2.5

0.09

NT-proBNP, pg/mL

1231.9 ± 2136.5

2425.4 ± 4459.3

 < 0.01*

Development of CADs, n (%)

39 (14.9%)

117 (35.1%)

 < 0.01*

  1. mean ± standard deviation or number (%). *means statistically significant; p values < 0.05
  2. IVIG Intravenous immunoglobulin, WBC White blood cells, ANC Absolute neutrophil counts, AST Aspartate aminotransferase, ALT Alanine transaminase, CRP C-reactive protein, NT-proBNP Nitrogen terminal-pro brain natriuretic peptide, CAD Coronary artery dilatation