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Table 2 Correlation analysis between serum neurofilament light (NfL) levels and other parameters

From: Serum neurofilament light reflects cognitive dysfunctions in children with obstructive sleep apnea

Variables

NfL levels

Spearman correlation

P

Course of snoring

0.354

< 0.001***

Course of mouth breathing

0.193

0.049*

Course of choking

0.313

0.001**

A/N

0.395

< 0.001***

Tonsil size

0.260

0.007**

AHI

0.647

< 0.001***

OAI

0.452

< 0.001***

OAHI

0.631

< 0.001***

Minimum SaO2

-0.430

< 0.001***

RAI

0.504

< 0.001***

VIQ

-0.447

< 0.001***

PIQ

-0.480

< 0.001***

FIQ

-0.388

< 0.001***

  1. A/N Adenoidal hypertrophy/nasopharyngeal cavity, AHI Apnea–hypopnea index, OAI Obstructive apnea index, OAHI The obstructive apnea–hypopnea index, SaO2 Arterial oxygen saturation, RAI Respiratory arousal index, VIQ Verbal IQ, PIQ Performance IQ, FIQ Full-Scale IQ. Tonsil size: Grade 0, tonsils restricted into the tonsil fossae; Grade 1, tonsils sitting just outside of the tonsillar fossa and occupying ≤ 25% of the area between the tonsillar pillars; Grade 2, tonsils seen in the airway and occupying 25-50% of the area between the pillars; Grade 3, tonsils occupying 50%-75% of the area between the pillars; and grade 4, tonsils occupying > 75% of the area between the pillars. ***P < 0.001, **P < 0.01, *P < 0.05