Safety and tolerance assessment of milk fat globule membrane-enriched infant formulas in healthy term Chinese infants: a randomised multicenter controlled trial

Table 6 Weight gain and increases in length, head circumference, and body mass index (BMI) between three groups of infants during 0 – 42 days of age

		MFGM-enriched formula			Standard formula			P²	Breast-fed reference			P²
	Gender	n	Mean	SD	n	Mean	SD	MF vs SF	n	Mean	SD	Overall
Weight (g/d)		108	38.49	8.85	104	37.10	8.59	0.91	206	41.98	10.14	< 0.001
	M	53	42.43	7.80	49	40.16	7.66	0.68	103	46.21	9.55	0.001
	F	55	34.56	8.04	55	34.12	8.40	1.00	103	37.83	8.92	0.022
Recumbent length (mm/month)		108	43.90	12.70	104	44.17	11.93	1.00	206	46.02	12.19	0.24
	M	53	47.76	12.11	49	47.76	11.96	1.00	103	50.11	12.06	0.42
	F	55	40.03	12.09	55	40.66	10.82	1.00	103	42.01	10.91	0.57
Head circumference (mm/month)		108	23.75	9.86	104	24.63	9.87	1.00	206	24.28	9.91	0.57
	M	53	26.05	10.18	49	25.67	9.91	0.63	103	25.50	10.17	0.27
	F	55	21.44	8.96	55	23.62	9.72	0.84	103	23.08	9.49	0.50
BMI (kg/m²/month)		108	1.76	0.92	104	1.58	0.89	0.64	206	1.96	1.01	0.008
	M	53	1.89	0.81	49	1.64	1.03	0.69	103	2.13	1.05	0.026
	F	55	1.64	1.01	55	1.53	0.73	1.00	103	1.79	0.94	0.26

¹ A general linear model, group and sex as fixed effects and site as a random factor with post hoc Bonferroni adjusted comparisons when overall comparison was significant
² M males
³ F females

ISSN: 1471-2431