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Table 3 Associations between deprivation indices and congenital heart disease by rural or urban residence

From: Associations of congenital heart disease with deprivation index by rural-urban maternal residence: a population-based retrospective cohort study in Ontario, Canada

Variable

Urban residence

Rural residence

Adjusted OR

Adjusted OR

Material deprivation indexa

 1 (lowest)

Reference

Reference

 2

1.07 (0.99–1.16)

0.93 (0.77–1.13)

 3

1.11 (1.03–1.2)

1.17 (0.97–1.41)

 4

1.16 (1.07–1.25)

1.04 (0.84–1.28)

 5 (highest)

1.20 (1.11–1.29)

1.30 (1.06–1.61)

Social deprivation indexb

 1 (lowest)

Reference

Reference

 2

1.09 (1.00–1.18)

1.01 (0.86–1.19)

 3

1.06 (0.98–1.15)

0.96 (0.81–1.14)

 4

1.11 (1.03–1.19)

1.00 (0.80–1.25)

 5 (highest)

1.20 (1.11–1.29)

0.68 (0.37–1.24)

Maternal age at birth

  < 30 years

Reference

Reference

 30–34 years

0.99 (0.94–1.05)

1.05 (0.91–1.2)

  > 35 years

1.25 (1.18–1.33)

1.4 (1.20–1.64)

Obesity

 Yes

1.29 (1.22–1.37)

1.15 (0.99–1.32)

 No

Reference

Reference

 Unknown

1.13 (1.06–1.22)

1.10 (0.90–1.34)

ART derived pregnancy

 Yes

1.16 (1.03–1.30)

0.90 (0.62–1.32)

 No

Reference

Reference

Smoking, alcohol or drug use during pregnancy

 Yes

1.31 (1.23–1.4)

1.25 (1.08–1.44)

 No

Reference

Reference

All types of mental health illness in pre-pregnancy or during pregnancy

 Yes

1.22 (1.15–1.30)

1.26 (1.10–1.45)

 No

Reference

Reference

Pre-pregnancy maternal health conditions

 Yes

1.74 (1.66–1.83)

1.68 (1.48–1.92)

 No

Reference

Reference

Infant sex

 Male

1.09 (1.04–1.14)

1.21 (1.07–1.36)

 Female

Reference

Reference

  1. a p trend (Cochran–Armitage test) is 0.002 for rural area and < 0.0001 for urban area
  2. b p trend (Cochran–Armitage test) is 0.98 for rural area and < 0.0001 for urban area