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Table 3 Statistical characteristics of MMP7 and GGT

From: Serum matrix metalloproteinase-7 levels in infants with cholestasis and biliary atresia

 

AUC

95% CI

P-value

Cutoff

Sensitivity (%)

Specificity (%)

Youden index

PPV

NPV

MMP7 (ng/mL)

0.988 ± 0.008

0.972—1

 < 0.001

7.8

95.5

94.5

0.844

81.82

93.75

GGT (U/L)

0.854 ± 0.052

0.751—0.956

 < 0.001

434.5

77.3

77.8

0.551

71.27

77.8

  1. Abbreviation: GGT Gamma-glutamyl transferase, MMP7 matrix Metalloproteinase-7, PPV Positive predicted value, NPV Negative predicted value, AUC Area under ROC curve
  2. Youden index = Sensitivity + Specificity
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BMC Pediatrics

ISSN: 1471-2431

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