| Diagnosis | |
---|
| Biliary atresia | healthy | non-BA cholestasis | P-valuea |
---|
Bilirubin total (mg/dl) | 14.48 ± 4.84 | ___ | 13.88 ± 4.89 | 0.669 |
Bilirubin direct (mg/dl) | 6.89 ± 3.54 | ___ | 5.72 ± 2.75 | 0.187 |
AST (U/L) | 202.75 ± 89.14 | ___ | 285.77 ± 197.63 | 0.085 |
ALT(U/L) | 119.1 ± 58.78 | ___ | 173 ± 120.58 | 0.070 |
ALP(U/L) | 1765.1 ± 830.55 | ___ | 1042.21 ± 787.29 | 0.004 |
GGT(U/L) | 551.73 ± 208.17 | 149.71 ± 58.53 | 274.04 ± 163.43 | < 0.001* |
Hemoglobin | 13.54 ± 1.54 | ___ | 13.1 ± 2.21 | 0.441 |
MCV | 91.24 ± 2.74 | ___ | 119.14 ± 165.9 | 0.446 |
WBC | 8311.9 ± 2903.23 | ___ | 7243.9 ± 3098.28 | 0.220 |
PLT | 295,000 ± 130,000.38 | ___ | 323,433.33 ± 165,451.04 | 0.514 |
MMP7 (ng/mL) | 15.91 ± 6.64 | 0.49 ± 0.33 | 4.73 ± 2.59 | < 0.001# |
- Abbreviation: AST Aspartate aminotransferase, ALT Alanine aminotransferase, ALP Alkaline phosphatase, GGT Gamma-glutamyl transferase, MCV Mean corpuscular volume, WBC White blood cells, PLT Platelet (Thrombocyte) count, MMP7 matrix Metalloproteinase-7
- a Obtained from ANOVA for continuous variables. Values are mean ± SD (95% CI) or n (%)
- * Significant differences between the Biliary atresia and healthy groups (Pvalue < 0.001) and between the Biliary atresia and non-BA cholestasis groups (Pvalue < 0.001) and also between the healthy and non-BA cholestasis groups (Pvalue = 0.002) using Bonferroni test
- # Significant differences between the Biliary atresia and healthy groups (Pvalue < 0.001) and between the Biliary atresia and non-BA cholestasis groups (Pvalue < 0.001) and also between the healthy and non-BA cholestasis groups (Pvalue < 0.001) using Bonferroni test
- A significance level of 0.05 was considered (Pvalue < 0.05)