Table 2 Multiple linear regression analysis assessed association between study variables and the final height in different groups of CKD girls with short stature and delayed puberty
Variables | Univariable linear regression Beta (95%CI) | P value | Adjusted modela Beta (95%CI) | P value | Backward linear regression Beta (95%CI) | P value |
|---|---|---|---|---|---|---|
Groups | −4.29 (−5.02/−3.57) | < 0.001 | −0.79 (− 4.41/2.82) | 0.657 | – | – |
Age of starting GH | 0.19 (0.04/0.33) | 0.012 | −0.042(− 0.18/0.09) | 0.549 | – | – |
Height of starting GH | 0.18 (−0.008/0.38) | 0.06 | 0.27 (0.05/0.48) | 0.016 | 0.22 (0.09/0.35) | 0.001 |
Paternal Height | 0.29 (0.02/0.55) | 0.034 | 0.15 (0.03/0.27) | 0.013 | 0.14 (0.04/0.25) | 0.009 |
MPH | 0.14 (−0.21/0.51) | 0.419 | – | – | – | – |
Maternal Height | −0.07 (− 0.38/0.23) | 0.648 | – | – | – | – |
Duration of GH Therapy | – | – | – | – | – | – |
Duration of GH Therapy before starting EE | −0.12 (− 0.19/− 0.06) | < 0.001 | 0.07 (0.007/0.14) | 0.033 | 0.07(0.007/0.14) | 0.031 |
Age of starting EE | −0.15 (− 0.21/− 0.10) | < 0.001 | −0.23 (− 0.41/− 0.05) | 0.011 | −0.26 (− 0.37/− 0.15) | < 0.001 |
Height of starting EE | −0.14 (− 0.24/− 0.04) | 0.005 | 0.20 (− 0.003/0.4) | 0.053 | 0.19 (0.01/0.37) | 0.035 |
Duration GH therapy after starting EE | 0.15 (0.09/0.22) | < 0.001 | 0.12 (0.03/0.22) | 0.011 | 0.11 (0.02/0.20) | 0.011 |
Age of Discontinuing GH | 0.07 (−0.09/0.23) | 0.395 | – | – | – | – |