|
Variables
|
Group 1 (n = 16)
|
Group 2 (n = 22)
|
Group 3 (n = 21)
|
P value
|
|---|
|
FH (cm)
|
154.5 ± 1.4a
|
151.6 ± 2.3b
|
146.1 ± 2.3c
|
< 0.001
|
|
FH SD scorea
|
−1.14 ± 0.22a
|
−1.59 ± 0.36b
|
−2.44 ± 0.36c
|
< 0.001
|
|
MPH (cm)
|
159.5 ± 2
|
161.3 ± 3.2
|
160.3 ± 3
|
0.15
|
|
GH therapy before EE (month)
|
37.8 ± 6
|
52.9 ± 8
|
–
|
–
|
|
Lumbar (L1-L4) Density Z Score
|
|
Primary
|
−3 ± 0.5
|
–
|
–
| |
|
Final
|
−2.3 ± 0.3a
|
−2.8 ± 0.5b
|
−3.1 ± 0.6b
|
< 0.001
|
|
Femur Head Density Z Score
|
|
Primary
|
−3.5 ± 0.7
|
−3.4 ± 0.7
|
–
|
–
|
|
Final
|
− 2.6 ± 0.4a
|
−2.9 ± 0.4a
|
−3.5 ± 0.5b
|
< 0.001
|
|
Ca (mg/dl)
|
|
Primary
|
8.7 ± 0.2
|
8.7 ± 0.2
|
–
|
–
|
|
Final
|
8.8 ± 0.1a
|
8.7 ± 0.2a
|
8.4 ± 0.2b
|
< 0.001
|
|
Ph (mg/dl)
|
|
Primary
|
6.9 ± 0.4
|
6.7 ± 0.5
|
–
|
–
|
|
Final
|
6.2 ± 0.3a
|
5.9 ± 0.3b
|
7.4 ± 0.4c
|
< 0.001
|
|
PTH (pg/ml)
|
|
Primary
|
166 ± 0.2
|
176 ± 0.1
|
–
|
–
|
|
Final
|
143 ± 27a
|
155 ± 27a
|
279 ± 49b
|
< 0.001
|
|
FeP (%)
|
|
Primary
|
4.6 ± 0.1
|
4.9 ± 0.1
|
–
|
–
|
|
Final
|
8.3 ± 1.9
|
8.6 ± 2.5
|
8.4 ± 0.2
|
0.862
|
- One-Way ANOVA was used for Value analysis
- Value presented as mean ± SD
- In each row dissimilar values (a, b, c) are significantly different
- aFinal Height SD score according to the CDC growth chart for stature of 2-20 years old girls
