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Table 2 Effect of the different interventions in the biochemical outcomes

From: Effect of physical therapy on bone remodelling in preterm infants: a multicenter randomized controlled clinical trial

 

EGrlt

(n = 31)

EGpmc

(n = 31)

CG

(n = 34)

Pairwise comparation

Mean differences

CI95%

Lower bound

Upper bound

NTx-urine (nm of BCE / mm of creatinine)

Pre-treatment

4266.11 ± 1441.48

5409.33 ± 2724.29

4604.38 ± 1918.98

EGrlt = EGpmc

-1143.2

-2435.8

149.36

EGrlt = CG

-338.3

-1611.1

934.58

EGpmc = CG

805

-467.9

2077.8

2 weeks

5362.30 ± 2257.88

5759.57 ± 4094.29

4835.02 ± 2290.11

EGrlt = EGpmc

-397.3

-2245.6

1451.1

EGrlt = CG

527.3

-1292.81

2347.4

EGpmc = CG

924.5

-895.5

2744.6

Post-treatment

5070.38 ± 2807.67

5529.16 ± 4016.74

4317.45 ± 2231.91

EGrlt = EGpmc

-458.8

-2369.2

1451.6

EGrlt = CG

752.9

-1128.3

2634.2

EGpmc = CG

1211.7

-669.5

3092.9

NTx-serum (nm of BCE)

Pre-treatment

457.01 ± 109.59

473.38 ± 95.84

487.71 ± 107.05

EGrlt = EGpmc

-16.37

-122.31

89.6

EGrlt = CG

-30.7

-130.08

68.7

EGpmc = CG

-14.33

-120.27

91.61

Post-treatment

509.53 ± 98.3

494.63 ± 85.96

473.09 ± 80.11

EGrlt = EGpmc

14.9

-74.54

104.34

EGrlt = CG

36.44

-47.46

120.34

EGpmc = CG

21.54

-67.9

111

Beta-CTx (ng/ml)

Pre-treatment

0.79 ± 0.21

0.95 ± 0.31

0.91 ± 0.32

EGrlt = EGpmc

-0.16

-0.45

0.13

EGrlt = CG

-0.122

-0.4

0.15

EGpmc = CG

0.038

-0.25

0.33

Post-treatment

0.87 ± 0.19

0.94 ± 0.22

0.88 ± 0.26

EGrlt = EGpmc

-0.065

-0.29

0.16

EGrlt = CG

-0.005

-0.22

0.21

EGpmc = CG

0.059

-0.17

0.29

OC (ng/ml)

Pre-treatment

61.56 ± 28.11

78.1 ± 34.44

78.18 ± 31.51

EGrlt = EGpmc

-16.543

-48.1

14.97

EGrlt = CG

-16.62

-46.74

13.5

EGpmc = CG

-0.077

-32.12

31.97

Post-treatment

99.74 ± 34.05

97.35 ± 36.44

86.12 ± 24.52

EGrlt = EGpmc

2.397

-29.8

34.6

EGrlt = CG

13.62

-17.16

44.4

EGpmc = CG

11.222

-21.52

43.96

  1. *p < 0.05 for differences between groups. CG  Control Group, EGpmc  Experimental group treated with passive mobilizations with gentle joint compression, EGrlt  Experimental group treated with reflex locomotion therapy, CI95%  95% Confidence Interval, NTx N-Telopeptides of collagen bonds. Beta-CTx: C-telopeptides of collagen bonds, OC Osteocalcin, nm Nanometres, mm Millimetres, BCE Bone collagen equivalents, ng Nanogram, ml Millilitres. Data is presented as Mean ± SD