Table 1 Prevalence of viral load (VL) ≥ 1000 copies/mL at enrolment and 48 weeks by participant characteristics
Characteristic | All participants | VL ≥ 1000 copies/mL at enrolment | VL ≥ 1000 copies/mL at 48 weeks | ||||
|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | ||
Total | 347 | 151/345 | 43.8% | 114/315 | 36.2% | ||
Country | Zimbabwe | 241 | 69.5% | 100/241 | 41.5% | 79/224 | 35.3% |
Malawi | 106 | 30.5% | 51/104 | 49.0% | 35/91 | 38.5% | |
Trial arm | Control | 174 | 50.1% | 80/174 | 46.0% | 56/154 | 36.4% |
Intervention | 173 | 49.9% | 71/171 | 41.5% | 58/161 | 36.0% | |
Sex | Male | 177 | 51.0% | 82/177 | 46.3% | 53/166 | 31.9% |
Female | 170 | 49.0% | 69/168 | 41.1% | 61/149 | 40.9% | |
Age at enrolment, years | 6–10 | 47 | 13.5% | 17/47 | 36.2% | 9/44 | 20.5% |
11–15 | 158 | 45.5% | 69/156 | 44.2% | 48/143 | 33.6% | |
16–19 | 142 | 40.9% | 65/142 | 45.8% | 57/128 | 44.5% | |
ART regimen at enrolment | 1st line (NNRTI) | 258 | 74.6% | 110/256 | 43.0% | 83/236 | 35.2% |
2nd line (PI) | 86 | 24.9% | 41/86 | 47.7% | 31/76 | 40.8% | |
3rd line | 2 | 0.6% | 0/2 | 0.0% | 0/2 | 0.0% | |
Unknown | 1 | ||||||
Timing of regimen dosing | Once daily | 156 | 45.0% | 71/156 | 45.5% | 61/141 | 43.3% |
Twice daily | 191 | 55.0% | 80/189 | 42.3% | 53/174 | 30.5% | |
Duration on ART | < 2y | 33 | 9.8% | 7/32 | 21.9% | 7/30 | 23.3% |
2-5y | 130 | 38.6% | 56/129 | 43.4% | 40/120 | 33.3% | |
6-10y | 126 | 37.39% | 58/126 | 46.0% | 48/115 | 41.7% | |
> 11y | 48 | 14.24% | 24/48 | 50.0% | 18/41 | 43.9% | |
Missing | 10 | ||||||
Baseline viral load, copies/mL | < 50 | 105 | 30.4% | - | 11/94 | 11.7% | |
50–999 | 89 | 25.8% | - | 16/83 | 19.3% | ||
≥ 1000 | 151 | 43.8% | - | 87/136 | 64.0% | ||
Missing | 2 | ||||||
Baseline CD4 count, cells/µL | < 200 | 34 | 9.8% | 29/34 | 85.3% | 18/31 | 58.1% |
200–499 | 96 | 27.7% | 54/95 | 56.8% | 49/87 | 56.3% | |
≥ 500 | 217 | 62.5% | 68/216 | 31.5% | 47/197 | 23.9% | |
Previous history of TB | No | 249 | 72.0% | 103/247 | 41.7% | 75/223 | 33.6% |
Yes | 97 | 28.0% | 48/97 | 49.5% | 39/91 | 42.9% | |
Missing | 1 | ||||||
Currently in school | Yes | 285 | 83.1% | 120/284 | 42.3% | 91/262 | 34.7% |
No | 58 | 16.9% | 30/58 | 51.7% | 23/50 | 46.0% | |
Missing | 4 | ||||||
Ever repeated a grade in school | No | 142 | 41.9% | 57/142 | 40.1% | 40/133 | 30.1% |
Yes | 197 | 58.1% | 91/196 | 46.4% | 73/176 | 41.5% | |
Missing | 8 | ||||||
Education level of mother | No schooling | 22 | 7.3% | 12/22 | 54.5% | 44,186 | 57.1% |
Primary | 59 | 19.5% | 28/58 | 48.3% | 22/50 | 44.0% | |
Secondary | 213 | 70.5% | 80/212 | 37.7% | 63/200 | 31.5% | |
Tertiary | 8 | 2.7% | 4/8 | 50.0% | 2/8 | 25.0% | |
Missing | 45 | ||||||
Adherence | Adherent | 249 | 73.5% | 102/249 | 41.0% | 83/244 | 34.0% |
Non-adherent | 90 | 26.6% | 44/90 | 50.0% | 27/64 | 42.2% | |
Missing | 8 | 5/8 | 62.5% | 4/7 | 57.1% | ||
Unscheduled clinical visit for illness during follow-up | No | 274 | 84.5% | 104/272 | 38.2% | 86/266 | 32.3% |
Yes | 50 | 15.5% | 34/50 | 68.0% | 28/49 | 57.1% | |
Missing | 23 | ||||||