Fig. 2

A Gene Ontology (GO) [Metascape analysis (http://metascape.org/)]annotation histogram of downregulated gene enrichment. B GO annotation histogram of upregulated gene enrichment. Red represents the type of enrichment at the BP level of GO, green represents the type of enrichment at the CC level, and blue represents the type of enrichment at the MF level. BP: Gene ontology biological processes, biological processes completed through a variety of molecular activities; CC: Gene ontology cellular component, the cell structure position of gene products when performing functions; MF: Gene ontology molecular function, the activity of a single gene product (including protein or RNA) or a complex of multiple gene products at the molecular level. C Kyoto Encyclopedia of Genes and Genomes (KEGG) annotation histogram of downregulated gene enrichment. D KEGG annotation histogram of upregulated gene enrichment. The vertical coordinate represents the KEGG pathway enriched by differentially expressed genes, and the horizontal coordinate indicates the degree of enrichment of differentially expressed genes. The higher the score, the higher the concentration