Application of coagulation parameters at the time of necrotizing enterocolitis diagnosis in surgical intervention and prognosis

Table 4 Predictive values of coagulation parameters for surgical NEC

Variables	The best cut-off level	Youden index (largest)	Sensitivity (%)	Specifificity (%)	PPV (%)	NPV (%)
PT (s)	16.7	0.49	65.22	83.82	73.17	78.08
PT-INR	1.23	0.29	34.78	94.20	80.00	68.09
APTT (s)	41.3	0.54	67.39	86.76	77.50	79.73
Fib (g/L)	1.09	0.35	50.00	85.29	65.52	68.24
PLT (× 10⁹/L)	252	0.47	67.39	79.41	69.77	77.46

NEC Necrotizing Enterocolitis, PPV Positive Predictive Value, NPV Negative Predictive Value, PPV and NPV were calculated for the best cut-off levels. PT Prothrombin Time, PT-INR PT International Normalized Ratio, APTT Activated Partial Thromboplastin Time, Fib Fibrinogen, PLT Platelet Count

ISSN: 1471-2431