Naranjo’s scale | ||||
---|---|---|---|---|
Question | Yes | No | Don’t know | Score for hypertension |
1. Are there previous conclusive reports on this reaction? | + 1 | 0 | 0 | 0 |
2. Did the adverse event appear after the suspect drug was administered? | + 2 | -1 | 0 | + 2 |
3. Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered? | + 1 | 0 | 0 | + 1 |
4. Did the adverse reaction reappear when the drug was re-administered? | + 2 | -1 | 0 | + 2 |
5. Are there alternate causes (other than the drug) that could have solely caused the reaction? | -1 | + 2 | 0 | + 2 |
6. Did the reaction reappear when a placebo was given? | -1 | + 1 | 0 | +1 |
7. Was the drug detected in the blood (or other fluids)in a concentration known to be toxic? | + 1 | 0 | 0 | 0 |
8. Was the reaction more severe when the dose was increased or less severe when the dose was decreased? | + 1 | 0 | 0 | + 1 |
9. Did the patient have a similar reaction to the same or similar drugs in any previous exposure? | + 1 | 0 | 0 | 0 |
10. Was the adverse event confirmed by objective evidence? | + 1 | 0 | 0 | + 1 |
Total | + 10 |