Skip to main content

Table 3 The treatment protocol and laboratory test of infants with or without red blood cell transfusion post diagnosis of NEC

From: Red blood cell transfusions post diagnosis of necrotizing enterocolitis and the deterioration of necrotizing enterocolitis in full-term and near-term infants: a propensity score adjustment retrospective cohort study

Variables

Red Blood Cell Transfusion post NEC diagnosis

With (n = 60)

Without (n = 182)

P

Albumin transfusion, %(n)

68.3 (41)

29.7 (54)

0.000

Transfusion prior to NEC diagnosis, %(n)

16.7 (10)

2.7 (5)

0.000

Fresh frozen plasma transfusion post NEC diagnosis, %(n)

25.0 (15)

2.2 (4)

0.000

Platelet transfusion post NEC diagnosis, %(n)

11.7 (7)

1.6 (3)

0.003

Cryoprecipitate transfusion post NEC diagnosis, %(n)

16.7 (10)

4.4 (8)

0.004

Intravenous immunoglobulin, %(n)

15.0 (9)

3.8 (7)

0.007

Probiotics use, %(n)

48.3 (29)

50.5 (92)

0.766

Anaerobic antimicrobial therapy, %(n)

90.0 (54)

62.6 (114)

0.000

Vasoactive agents support, %(n)

41.7 (25)

17.0 (31)

0.000

Mechanical ventilation, %(n)

6.7(4)

0(0)

0.001

Broad spectrum antibiotics use [days, median (IQR)]

18 (12–24)

12 (9–16)

0.000

Cessation of enteral feeding [days, median (IQR)]

8.5 (6–13.75)

7 (4–9)

0.000

Gastrointestinal decompression [days, median (IQR)]

6 (1.25–9)

1 (0–4.25)

0.000

WBC counta < 5 × 109/L or > 20 × 109/L, %(n)

20.0 (12)

15.9 (29)

0.467

Platelet counta < 100 × 109/L, %(n)

11.7 (7)

7.7 (14)

0.343

CRPa > 8 mg/L, %(n)

46.7 (28)

27.5 (50)

0.006

Lowest Hct b (%, mean ± SD)

25.8 ± 4.1

35.1 ± 6.4

0.000

  1. aThe baseline values were tested within 24 h of NEC diagnosis
  2. bThe Lowest Hct post NEC diagnosis and prior NEC deterioration
  3. WBC White blood cell, CRP C-reactive protein, NEC Necrotizing enterocolitis, Hct Hematocrit, SD Standard deviation, IQR Interquartile range