Skip to main content

Table 1 Important risk factors associated with development of orofacial clefts

From: The characteristics and perioperative outcomes of children with orofacial clefts managed at an academic hospital in Johannesburg, South Africa

Risk factor

n (%)

Family history and genetic factors

18(10)

Alcohol use during pregnancy

4(2)

Tobacco use during pregnancy

9(5)

Medications taken during pregnancy

1(0.6)

Maternal infections during pregnancy

29(17)

Maternal age over 35 years

16(9)

Low socioeconomic status

62(35)

Use of illicit drugs during pregnancy

2(2)

Antenatal vitamin and mineral supplements

56(32)