Table 2 Inclusion/Exclusion criteria for eligible studies
Studies included | Studies excluded |
|---|---|
● Studies with Case–control designs ● Report of the association between the MTHFR C677T, MTHFR G1793A and MS A2756G polymorphism and the risk of CHD ● Studies that included Pediatric participants ● Studies that follow Hardy Weinberg equilibrium (HWE) ● Studies with sufficient data ● Studies in English language | ● Case reports ● Meta analysis and review articles ● Studies without control group ● Studies with abstract only ● Studies that include maternal/ paternal cases only ● Studies without detailed genotype data ● Studies that are associated with other diseases like CVD’s, thrombosis, coronary artery defects etc |