Table 4 Multivariable patient and pathogen predictors of antimicrobial treatment duration
Predictor | Adjusted beta coefficient | 95% CI | p-value |
|---|---|---|---|
Age in years | -0.1 | -0.6 to + 0.3 | 0.62 |
PRISM-IV score |  + 0.4 |  + 0.1 to + 0.7 | 0.007 |
Comorbidities | |||
 Cardiovascular | -0.4 | -4.7 to + 3.9 | 0.85 |
 Respiratory | -1.4 | -6.4 to + 3.6 | 0.58 |
 Neurologic | -1.9 | -8 to + 4.2 | 0.54 |
 Immunosuppressed | -2.4 | -7.3 to + 2.6 | 0.34 |
Pathogen group | |||
 Staphylococcus aureus |  + 1.7 | -6.2 to + 9.5 | 0.68 |
 Enterococcus species |  + 0.3 | -7.1 to + 7.7 | 0.93 |
 Other staphylococci/CONS | -6.2 | -15.4 to + 3 | 0.19 |
 Streptococcus species | -0.7 | -7.6 to + 6.3 | 0.85 |
 Other Gram negative bacteria |  + 2.5 | -4.3 to + 9.3 | 0.47 |
 Other Gram positive bacteria | -8.6 | -19.1 to + 1.8 | 0.11 |
 Candida species |  + 5.3 | -6.7 to + 17.3 | 0.38 |
 Polymicrobial |  + 0.4 | -7.2 to + 8 | 0.92 |
 Enterobacterales | reference | – | – |
Underlying source | |||
 Vascular catheter | -1.4 | -6.9 to + 4.1 | 0.62 |
 Respiratory | -1.8 | -7.8 to + 4.3 | 0.57 |
 Urinary |  + 1.2 | -7.6 to + 9.9 | 0.79 |
 Intra-abdominal |  + 4.1 | -2.4 to + 10.7 | 0.22 |
 Skin/soft tissue |  + 0.9 | -6.2 to + 8 | 0.8 |
 CNS |  + 17 |  + 6.7 to + 27.4 | 0.001 |
 Othera |  + 19.2 |  + 7.6 to + 30.8 | 0.001 |
 Unclear | -4.4 | -11.1 to + 2.3 | 0.2 |