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Table 3 Infection characteristics and treatment duration

From: Antimicrobial treatment duration for uncomplicated bloodstream infections in critically ill children: a multicentre observational study

Characteristic

n (%)

Median (days)

IQR (days)

p-valuea

Pathogen

 Staphylococcus aureus

29 (13)

17

13–32

0.03b

 Enterococcus species

27 (12)

16

11–30

 Other staphylococci, including CONS

19 (8)

11

7–13

 Streptococcus species

   S. pneumoniae

10 (4)

15

12–29

   Group B streptococcus

7 (3)

11

5–15

   Group A streptococcus

6 (3)

15.5

11–51

   Other streptococci

12 (5)

11

9.5–15.5

 Klebsiella species

23 (10)

16

11–26

 Escherichia coli

18 (8)

16

12–23

 Enterobacter cloacae

16 (7)

17

15–21.5

 Pseudomonas species

11 (5)

17

15–26

 Other Gram negative bacteria

25 (11)

19

11–30

 Other Gram positive bacteria

13 (6)

12

7–15

 Candida species

9 (4)

30

17–34

Underlying source

  Vascular catheter

   

0.81

    Yes

77 (41)

16

11–24

    No

110 (59)

15

11–25

  Respiratory

   

0.74

    Yes

34 (18)

15

11–26

    No

153 (82)

15

11–23

  Intra-abdominal

   

0.04

    Yes

22 (12)

20

14–26

    No

165 (88)

15

11–23

  Skin/soft tissue

   

0.02

    Yes

20 (11)

17

15–33

    No

167 (89)

15

11–23

  Urinary

   

0.34

    Yes

13 (7)

17

15–35

    No

174 (93)

15

11–24

  CNS

   

0.02

    Yes

7 (4)

33

15–46

    No

180 (96)

15

11–23

  Other source(s)c

   

0.07

    Yes

6 (3)

29.5

15–55

    No

181 (97)

15

11–23

  Unclear source

   

0.02

    Yes

37 (20)

13

10–16

    No

150 (80)

16

11–27

  1. IQR interquartile range, CONS coagulase negative staphylococci
  2. aWilcoxon rank sum
  3. bKruskal-Wallis test
  4. cOther sources: 3 retropharyngeal abscesses, 1 possibly related to cardiac surgery, 1 endovasculitis, 1 unspecified