Table 3 IO with pathogenic variants in HBB, HFE, TFR2, and SLC40A1 (Ferroportin) genes

Homozygotes

Number

32

0

0

0

Median serum ferritin

(ng/ml)

2546

-

-

-

Median Hepatic T2*

(ms)

4.1

-

- 

-

Median LIC

(mg/g)

6.45

-

-

-

Median Cardiac T2*

(ms)

20.6

-

-

-

Median MIC

(mg/g)

1.12

-

-

-

Compound

Number

18

0

0

0

Heterozygotes

Meadian serum ferritin

(ng/ml)

2490

-

-

-

Median Hepatic T2*

(ms)

4.8

-

-

-

Median LIC

(mg/g)

5.4

-

-

-

Median Cardiac T2*

(ms)

27.15

-

-

-

Median MIC

(mg/g)

0.82

-

-

-

Heterozygotes

Number

2

8

0

0

Median serum ferritin

(ng/ml)

-

1791.5

-

-

Median Hepatic T2*

(ms)

-

4.6

-

-

Median LIC

(mg/g)

- 

5.72

- 

- 

Cardiac T2*

(ms)

-

14.8

- 

-

Median MIC

(mg/g)

-

1.76

-

-