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Table 4 Risk factors for NEC

From: Development of necrotizing enterocolitis in full-term infants with duct dependent congenital heart disease

Variables

Univariate analysis

OR

95% CI

P-value

Sex, male

0.60

0.17–2.12

0.513

Gestational age

 38–42 weeks (ref)

   

 37–37 + 6 weeks

8.87

2.41–32.63

0.002

PGE1 infusion time

  < 1 week (ref)

   

 1–2 weeks

0.61

0.12–3.06

0.717

 2–4 weeks

1.10

0.13–9.44

1.000

  ≥ 4 weeks

2.56

0.28–22.97

0.375

Birth weight

  ≥ 2500 g (ref)

   

  < 2500 g

5.14

1.25–21.12

0.042

Nutrition

 Full enteral (ref)

   

 Partial or NPO

107.67

16.43–705.38

< 0.001

Type of DD-CHD

 DD-pulmonary (ref)

   

 DD-systemic

0.44

0.09–2.14

0.489

 Parallel

0.29

0.04–2.38

0.443

Functional single ventricle

5.78

1.59–21.05

0.009

Ventilator care

4.59

1.26–16.69

0.021

  1. NEC necrotizing enterocolitis, OR odds ratio, CI confidence interval, ref reference group, PGE1 prostaglandin E1, NPO nil per os, DD-CHD ductal-dependent congenital heart disease, DD ductal-dependent