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Table 3 Risk of bias assessment of six methodological domains as per the Cochrane risk-of-bias tool (v2.0)

From: Melatonin for pre-medication in children: a systematic review

  Random sequence generation (selection bias) Allocation concealment (selection bias) Blinding of participants (performance bias) Blinding of IMP administrators (performance bias) Blinding of outcome assessment (detection bias) Incomplete outcome data (attrition bias) Selective reporting (reporting bias)
Almenrader (2013) + + + + +
Ansari (2018) + / + + + +
Faghihian (2018) + + + / + / +
Gitto (2016) + + + + + / +
Impellizzeri (2017) + + + + + + +
Isik (2008) + / + / + + +
Kain (2009) + + + + + + +
Khalifa (2013) + + + / + + +
Kurdi (2016) + + + + + +
Ozcengiz (2011) + + + / + + +
Samarkandi (2005) + + + + + + +
  1. + Low risk of bias; / unspecified; − High risk of bias