The clinical effects of high-frequency oscillatory ventilation in the treatment of neonatal severe meconium aspiration syndrome complicated with severe acute respiratory distress syndrome

Table 2 Comparison of blood gas analysis and oxygen indexes between HFOV group (n=31) and CMV group (n=34) (\(\overline{x}\)±s)

	Before treatment	6 h after treatment	12 h after treatment	24 h after treatment	48 h after treatment	72 h after treatment
PaO₂
HFOV group	43.30±3.33	60.61±3.30	68.32±5.12	74.35±3.06	78.37±5.22	82.77±4.11
CMV group	44.41±2.83	57.26±4.83	65.00±7.06	70.56±6.81	74.41±4.57	82.44±6.82
t	-1.39	3.23	2.16	2.94	3.24	0.94
p	0.169	<0.01	0.035	<0.01	<0.01	0.349
PaCO₂
HFOV group	61.03±3.81	54.03±3.77	50.42±5.20	46.97±5.60	42.74±3.68	39.97±3.38
CMV group	61.65±3.59	57.09±5.46	54.44±3.70	51.41±5.03	46.91±5.41	41.24±4.06
t	-0.84	-2.60	-3.57	-3.436	-3.60	-1.36
p	0.403	0.012	<0.01	<0.01	<0.01	0.179
PaO₂/FiO₂
HFOV group	132.71±7.07	190.58±12.20	217.19±13.27	268.52±17.64	304.45±17.93	347.74±20.79
CMV group	130.32±6.41	182.21±16.46	209.47±12.65	253.71±17.82	285.91±33.49	338.03±17.44
t	1.43	2.34	2.40	3.36	2.82	2.05
p	0.158	0.022	0.019	<0.01	<0.01	0.045
OI
HFOV group	17.82±1.62	15.52±2.43	13.28±1.65	10.07±1.45	8.00±1.97	6.25±2.66
CMV group	17.33±2.35	16.64±1.41	14.19±1.55	11.19±1.46	9.12±1.29	7.29±1.32
t	1	-2.24	-2.27	-3.10	-2.83	-2.03
p	0.321	0.025	0.026	<0.01	<0.01	0.047

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