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Table 1 General characteristics

From: Brain and renal oxygenation measured by NIRS related to patent ductus arteriosus in preterm infants: a prospective observational study

 

noPDA (n = 64)

PDA (n = 41)

HsPDA (n = 18)

p value

Gestational age (weeks), mean (SD)1–3

28.5 (1.92)

27.2 (1.65)

25.8 (2.01)

< 0.001

Birth weight (g), mean (SD)1–3

1118.6 (221.03)

1009.5 (215.43)

839.4 (219.99)

< 0.001

Male, %

31 (48.4)

23 (56.1)

10 (55.6)

NS

Apgar at 1 min, mean (SD)

7 (1.62)

6.7 (1.82)

5.8 (2.28)

NS

Apgar at 5 min, mean (SD)

8 (1.41)

7.9 (1.19)

7.4 (1.33)

NS

Hours of life at measurement, mean (SD)2, 3

150.4 (45.3)

141.6 (36.7)

185.8 (58.0)

0.003

Haematocrit (%), mean (SD)2

46.03 (8.48)

43.67 (10.523)

38.71 (7.094)

0.011

Platelets (× 109/l), mean (SD)

269.19 (99.687)

254 (116.908)

258.44 (150.983)

NS

pCO2, mean (SD)

42.25 (6.816)

44.41 (9.25)

46.09 (10.912)

NS

Lactate (mmol/l), mean (SD)

1.94 (0.598)

2.15 (1.084)

2.06 (0.523)

NS

Urine output (ml/kg/h), mean (SD)

3.91 (0.796)

3.63 (0.971)

3.51 (0.899)

NS

Antenatal steroids 2x, %

42 (66.7)

32 (78.0)

13 (72.2)

NS

Chorioamnionitis, %

16 (25.8)

11 (28.9)

6 (35.3)

NS

Caesarean section, %

44 (68.8)

33 (80.5)

8 (44.4)

0.025

Surfactant, %

41 (64.1)

36 (87.8)

17 (94.4)

0.003

Mechanical ventilation, %

11 (17.2)

18 (43.9)

16 (88.9)

< 0.001

Non-invasive respiratory support, %

35 (54.7)

17 (41.5)

1 (5.6)

< 0.001

FiO2, mean (SD)2, 3

0.25 (0.05)

0.25 (0.05)

0.32 (0.09)

< 0.001

Ductus diameter (cm), mean (SD)3

0.17 (0.039)

0.26 (0.032)

< 0.001

LA/Ao ratio, mean (SD)1–3

1.24 (0.174)

1.38 (0.202)

1.72 (0.179)

< 0.001

RI ACA, mean (SD)1–3

0.7 (0.039)

0.74(0.061)

0.84 (0.144)

< 0.001

CROR, mean (SD)1, 2

0.97 (0.091)

0.90 (0.108)

0.87 (0.167)

0.001

  1. 1: Statistically significant difference between the “noPDA” and “PDA” groups
  2. 2: Statistically significant difference between the “noPDA” and “HsPDA” groups
  3. 3: Statistically significant difference between the “PDA” and “HsPDA” groups. NS: not significant