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Table 3 The effect (crude and adjusted ORs) of different characteristics on mortality in Iranian COVID-19 hospitalized children (N = 6610)

From: Red flags of poor prognosis in pediatric cases of COVID-19: the first 6610 hospitalized children in Iran

Characteristics

Crude OR (95%CI)

P-value

Adjusted (95%CI) OR

P-value

Demographics

 Age

1.01 (0.99-1.03)

0.166

1.01 (0.99-1.03) b

0.152

 Age < 1 year

Reference

–

Reference

–

  1-5 years

0.60 (0.44-0.81)

0.001

0.62 (0.44-0.87) b

0.006

  6-12 years

0.67 (0.49-0.92)

0.014

0.67 (0.47-0.96) b

0.029

  13-17 years

0.92 (0.68-1.25)

0.623

0.95 (0.68-1.34) b

0.766

 Sex

1.02 (0.82-1.27)

0.843

1.01 (0.80-1.28) b

0.932

Comorbidities

 Cardiovascular diseases

3.88 (2.60-5.80)

< 0.001

3.27 (2.09-5.11) c

< 0.001

 Diabetes

3.23 (1.88-5.56)

< 0.001

2.50 (1.38-4.55) c

0.003

 Chronic pulmonary diseases

3.92 (2.03-7.56)

< 0.001

3.21 (1.59-6.47) c

0.001

 Liver dysfunction

4.16 (1.70-10.16)

0.002

2.90 (0.96-8.84) c

0.06

 Kidney dysfunction

4.58 (2.47-8.49)

< 0.001

3.42 (1.75-6.67) c

< 0.001

 Malignancies

2.29 (1.21-4.33)

0.011

1.88 (0.88-3.98) c

0.101

 Immunodeficiency disorders

1.49 (0.46-4.85)

0.512

1.06 (0.29-3.89) c

0.925

Signs and symptoms

 No symptoms

1.36 (1.02-1.79)

0.033

1.36 (1.03-1.80) a

0.030

 Fever

0.58 (0.46-0.74)

< 0.001

0.59 (0.47-0.75) a

< 0.001

 Cough

1.15 (0.93-1.44)

0.201

1.14 (0.91-1.42) a

0.260

 Headache

0.39 (0.21-0.71)

0.002

0.36 (0.20-0.67) a

0.001

 Sore throat

1.24 (0.87-1.77)

0.238

1.21 (0.84-1.73) a

0.299

 Myalgia

0.64 (0.43-0.93)

0.020

0.60 (0.41-0.88) a

0.010

 Dyspnea

2.66 (2.15-3.31)

< 0.001

2.65 (2.13-3.29) a

< 0.001

 Diarrhea

0.24 (0.13-0.43)

< 0.001

0.24 (0.13-0.44) a

< 0.001

  1. aAdjusted for age and sex variables
  2. bAdjusted for all comorbidities
  3. cAdjusted for other comorbidities, sex and age