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Fig. 3 | BMC Pediatrics

Fig. 3

From: Clinical and genetic features of infancy-onset congenital myopathies from a Chinese paediatric centre

Fig. 3

Transverse sections of muscle specimens from patients with CNM and CFTD. (A, patient 15, left biceps) Central nuclei (arrows) appeared in more than 30% of fibres (haematoxylin and eosin staining). (B patient 15, left biceps) The intermyofibrillar network revealed by reduced nicotinamide adenine dinucleotide–tetrazolium reductase (NADH-TR) staining, showing radiates like spokes of a wheel from the centre to the periphery of the fibres (arrows). (C, patient 17, left biceps) Adenosine triphosphatase (ATPase) staining with preincubation at pH 4.6. Type 1 fibers (dark type) are at least 12% smaller than type 2 fibres (pale type) accompanied by type 1 fibre predominance

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