Study (year) Country | Study Design | Participant characteristics | Outcome assessment | ||||||
---|---|---|---|---|---|---|---|---|---|
Participants (n) | Drop out (%) | Age in years Mean (SD) % Female | Beighton scorea Mean (SD) | Recruitment site | Treatment or intervention group | Control group | Duration (Follow-up b) | ||
Bale et al. (2019) [39] UK | Randomised controlled trial | 119 baseline 111 At 3months 105 At 12 months | 7% 12% | 9.4 (3.2) 55% | 5.7 (1.4) | Children’s department at tertiary Hospital | therapy intervention (Tertiary PT and OT x5 sessions) | Standard care (medical assessment and allied health referrals) | 2 months (1, 10 months) |
Hsieh et al. (2018) [40] Taiwan | Randomised controlled trial | 52 Baseline 50 At 3 months | 4% | 6.6 (0.6) 46% | 7.5 (1.6) | Outpatient rehabilitation center – teaching hospital | Physical therapy & orthotics with customised insoles | Physical therapy & podiatry without customised insoles | 3 months |
Kemp et al. (2010) [41] UK | Randomised controlled trial | 57 Baseline 32 At 3 months | 44% | 10.9 (2.5) 33% | 5.8 (1.6) | Rheumatology Outpatient department | Psychosocial & physical therapy targeted to improve functional stability of symptomatic joints | Generalised therapy to improve muscle strength & fitness | 2 months (3months follow-up) |
Pacey et a1. (2013) [42] Australia | Randomised controlled trial | 29 Baseline 26 randomised 25 2 months | 14% | 12.1(2.9) 66% | 7.1 (1.2) | Physiotherapy department in a teaching hospital | Physical therapy: Muscle strength & motion control performed into full range of knee hyperextension | Physical therapy: Muscle strength & motion control performedinto knee extension neutral range | 2 week baseline without treatment followed by 8 treatment sessions and home exercises over 2 months |
Revivo et al. (2019) [43] UK | Pre-Post retrospective | 30 Baseline 26 2 months | 13% | 14.0 (2.8) 90% | >4 | Hospital Outpatient multidisciplinary pain management clinic | Physical therapy, occupational therapy, psychology counselling, & weekly paediatric rehabilitation follow-up | None | 1.5-2 months |
Scheper et al. (2017) [44] Australia | Observational longitudinal | 101 Baseline 81 3 years | 20% | 11.5 ± 3.1 55% | 7 ± 1.6 | Tertiary hospital Outpatients clinics | No restrictions on treatment of participants | None | 3 years |