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Table 22 Obstructive Genitourinary Defects - Comprehensive Cannabinoid Space – Time Regression Models

From: Geotemporospatial and causal inference epidemiological analysis of US survey and overview of cannabis, cannabidiol and cannabinoid genotoxicity in relation to congenital anomalies 2001–2015

Lagged Variables

Parameter

Model Parameters

Parameter

Estimate (C.I.)

P-Value

Parameter

Value

Model P-Value

 

Interactive Model - Including Sociodemographics

    

spreml(Rate ~ Cigarettes * THC * CBD + Analgesics + Bng.Alcohol + Cocaine + Income + 5_Races)

  

Hispanic

7.56 (3.56, 11.55)

0.0002

S.D.

2.3684

 

THC

37.58 (9.36, 65.79)

0.0090

LogLik

−254.1933

 

Am.Indian/Alaskan.Native

124.12 (30.78, 217.46)

0.0092

psi

0.9663

< 2.2e-16

THC: CBG

6.95 (0.33, 13.56)

0.0395

   

Income

−13.2 (−23.45, −2.94)

0.0117

   

1 Years Lag

     

Interactive Model - Including Sociodemographics

    

spreml(Rate ~ Cigarettes * THC * CBD + Analgesics + Bng.Alcohol + Cocaine + Income + 5_Races)

  

THC, 1

Hispanic

7.59 (3.07, 12.12)

0.0010

S.D.

3.2724

 

CBD, 1

Cigarettes: THC

46.25 (16.84, 75.67)

0.0021

LogLik

−187.7251

 

Am.Indian/Alaskan.Native

148.61 (47.3, 249.93)

0.0040

psi

0.9689

< 2.2e-16

Income

−17.24 (−30.36, −4.12)

0.0100

   

2 Years Lag

     

Interactive Model - Including Sociodemographics

    

spreml(Rate ~ Cigarettes * THC * CBD + Analgesics + Bng.Alcohol + Cocaine + Income + 5_Races)

  

THC, 2

Hispanic

12.81 (8.33, 17.3)

2.17E-08

S.D.

3.2724

 

CBD, 2

Cigarettes: THC: CBD

6151.83 (2693.75, 9609.91)

0.0005

LogLik

−187.7251

 

Cigarettes: THC

22,951.53 (9883.29, 36,019.77)

0.0006

psi

0.0000

NA

Cigarettes

15,335.11 (5177.59, 25,492.63)

0.0031

   

Cigarettes: CBD

4078.6 (1248.29, 6908.9)

0.0047

   

Am.Indian/Alaskan.Native

107.64 (18.06, 197.22)

0.0185

   

CBD

−894.76 (−1549.98, −239.53)

0.0074

   

Bng.Alcohol

−186.96 (−318.68, −55.23)

0.0054

   

THC

−5115.33 (−8111.04, −2119.62)

0.0008

   

THC: CBD

−1370.14 (−2158.79, −581.48)

0.0007