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Table 4 Comparison of Colombian data with other studies

From: Mortality and clinical characteristics of multisystem inflammatory syndrome in children (MIS-C) associated with covid-19 in critically ill patients: an observational multicenter study (MISCO study)

 

MISCO study

n (%)

MIS-C USA11 n (%)

P valuea

MIS-C UK10

n (%)

P valuea

Number of patients

78

570

 

52

 

Patients in PICU

78 (100)

364 (63.9)

 

38 (73)

 

Age in years (median, IQR)

7 (1 - 11)

8 (4 - 12)

 

4.6 (0.3 - 13.7)

 

Age

 

N/R

   

< 5 years

29/78 (37)

  

5/52 (10)

0.004

≥ 5 years

49/78 (63)

  

47/52 (90)

Sex

     

Male

46/78 (59)

316/570 (55)

0.55

31/52 (60)

0.94

Female

32/78 (41)

254/570 (45)

 

21/52 (40)

Obesity

23/78 (29.5)

146/570 (26)

0.46

5/51 (10)

0.008

Symptoms of KD

     

Fever

78/78 (100)

 

NA

52/52 (100)

NA

Changes in the mouth and mucous membranes

17/78 (22)

201/570 (35)

0.018

  

Lymphadenopathy

18/78 (23)

76/570 (13)

0.02

9/46 (19.5)

0.6

Conjunctival injection

23/78 (29.5)

276/570 (48)

0.001

20/48 (42)

0.16

Other symptoms

     

Diarrhea

55/78 (70.5)

303/570 (53)

0.001

32/49 (65)

0.53

Abdominal pain

55/78 (70.5)

353/570 (62)

0.14

34/50 (68)

0.76

Nausea/vomiting

58/78 (74)

352/570 (62)

0.03

38/50 (76)

0.83

Headache

17/78 (22)

186/570 (33)

0.052

16/47 (34)

0.13

Labs

     

Lymphopenia

50/78 (64)

202/570 (35)

0.001

  

Thrombocytopenia

28/78 (36)

176/570 (31)

0.37

16/50 (32)

0.65

Cardiac complications

     

Shock

68/78 (87%)

202/570 (35)

0.001

  

Elevated troponin

38/75 (51%)

176/570 (30.9)

0.006

  

Elevated BNP

27/33 (82%)

246/570 (43)

0.001

  

Cardiac dysfunction

14/75 (19)

207/510 (40.6)

0.002

  

Coronary dilation

19/75 (25)

95/510 (18.6)

0.17

10/37 (27)

0.31

Pericardial effusion

27/75 (36)

122/510 (23.9)

0.02

 

0.15

Mitral regurgitation

16/75 (21)

130/510 (25.5)

0.43

5/37 (13.5)

0.21

Hypotension

61/78 (78)

282/570 (49.5)

0.001

9/37 (24)

 

IVIG

71/78 (91)

424/570 (81)

0.001

28/43 (65)

0.004

Steroids

55/78 (70.5)

331/570 (63)

0.03

24/44 (55)

0.07

Mechanical ventilation

22/78 (28)

69/570 (13)

0.001

14/52 (27)

0.87

High-flow cannula

24/78 (31)

 

NA

23/52 (44)

0.11

Inotropic support

59/78 (76)

221/570 (42)

0.001

25/49 (51)

0.004

Death

7/78 (9)

10/570 (1.8)

0.001

0/51

NA

  1. a Chi square test or Fisher’s exact test, as applicable. KD: Kawasaki disease. N/R Not reported