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Table 1 Clinical details at diagnosis and during follow-up in patients with PIBD-related CRC

From: Colorectal Cancer associated with pediatric inflammatory bowel disease: a case series

Patient No. Patient 1 Patient 2 Patient 3 Patient 4
Sex M M M M
Age at first IBD diagnosis (years) 12 11 5 16
Year of first diagnosis 2000 2010 2001 2018
Type of IBD CD UC VEOIBD CD
Genetic findings NA NA Negative NA
Disease location (Paris classification) L3 E4 L3 L4
Perianal diseases Fistula Skin tag (−) (−)
Luminal complications Luminal stricture
Bowel obstruction
(−) (−) Luminal narrowing
Bowel obstruction
 Thiopurine (years) 9.43 2.05 2.48 0.42
 TNF inhibitor (years) (−) 3.44 (−) (−)
 Methotrexate (years) (−) 0.33 (−) (−)
 Other biologicals (years) (−) 0.71 (Golimumab) (−) (−)
Surgery before cancer diagnosis (−) (−) (−) (−)
 Age at cancer diagnosis (years) 24 20 15 17
 Location Transverse colon Sigmoid colon Ascending, sigmoid colon Sigmoid colon
 Histological type Mucinous carcinoma Adenocarcinoma Adenocarcinoma Signet ring carcinoma
 Stage according to AJCC 8th pT3N0M0 pT1N0M0 pT3N0M0 pT4aN2bM1
 Disease duration before cancer diagnosis (years) 11.96 8.9 9.93 0.44
 Last follow-up (year) 2020 (Ongoing) 2020 (Ongoing) 2020 (Ongoing) 2019 (Expired)
  1. IBD inflammatory bowel disease, TNF tumor necrosis factor, AJCC American Joint Committee on Cancer, NA not applicable