Association between early fluid overload and mortality in critically-ill mechanically ventilated children: a single-center retrospective cohort study

Table 6 Multivariate log regression analysis for association of %FO > 20% with in-hospital mortality

Outcome measure	β	OR	95% C.I.	P-value
No. of vasoactive drugs	0.385	1.469	1.079–2.000	0.014
Time of MV	−0.039	0.962	0.442–2.091	0.922
Duration of MV	0.046	1.047	1.018–1.076	0.001
Receipt of CRRT	−0.431	0.650	0.287–1.470	0.301
Diagnosis of MODS	1.733	5.656	2.591–12.345	< 0.001
Surgery	−0.886	0.412	0.185–0.916	0.030
FO > 20%	1.057	2.878	1.116–7.418	0.029
PRISM-III score	0.012	1.012	0.961–1.066	0.652

Hosmer–Lemeshow P = 0.625; predicted percentage was 80.9%. OR: odds ratio; 95%C.I.: 95% confidence interval; MV: mechanical ventilation; MODS: multiple organ dysfunction syndrome; CRRT: continuous renal replacement therapy; PRISM-III: third-generation admission pediatric risk of mortality score; FO: fluid overload. No.: number

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