Association between early fluid overload and mortality in critically-ill mechanically ventilated children: a single-center retrospective cohort study

Table 5 Multivariate log regression analysis for association of %FO > 10% with in-hospital mortality

Outcome measure	β	OR	95% C.I.	P-value
No. of vasoactive drugs	0.412	1.510	1.106–2.063	0.010
Time of MV	−0.043	0.958	0.444–2.065	0.913
Duration of MV	0.044	1.045	1.017–1.074	0.002
Receipt of CRRT	−0.343	0.710	0.314–1.603	0.409
Diagnosis of MODS	1.718	5.572	2.563–12.115	<0.001
Surgery	−0.886	0.412	0.188–0.904	0.027
FO > 10%	0.479	1.615	0.837–3.117	0.153
PRISM-III score	0.011	1.011	0.960–1.065	0.684

Hosmer–Lemeshow P = 0.894; predicted percentage 79.6%. OR: odds ratio; 95%C.I.: 95% confidence interval; MV: mechanical ventilation; MODS: multiple organ dysfunction syndrome; CRRT: continuous renal replacement therapy; PRISM-III: third-generation admission pediatric risk of mortality score; FO: fluid overload. No.: number

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