Table 1 Perinatal characteristics, short-term morbidities and neurodevelopmental outcomes of infants classified by presence of HsPDA
|  | Non-HsPDA n = 48 | HsPDA n = 124 | |
|---|---|---|---|
n (%)/mean ± SD | n (%)/mean ± SD | P value | |
GA (weeks) | 27.3 ± 0.8 | 26.2 ± 1.3 | 0.000 |
BW (g) | 1009.8 ± 212.1 | 889.6 ± 190.6 | 0.000 |
APGAR (5 min) < 7 | 10 (21.3) | 14 (11.9) | 0.12 |
CRIB II > 12 | 5 (10.6) | 33 (26.8) | 0.023 |
Severe RDS Grade 2–4 | 11 (22.9) | 85 (68.5) | 0.000 |
Surfactant Therapy > 2 doses | 1 (2.1) | 16 (12.9) | 0.033 |
Sepsis | 6 (12.5) | 38 (30.6) | 0.014 |
Severe IVH Grade 3–4 | 5 (10.4) | 25 (20.2) | 0.13 |
PVL | 1 (2.1) | 4 (3.2) | 0.69 |
NEC or NEC with complication/surgery | 0 (0.0) | 8 (6.5) | 0.07 |
Threshold ROP Stage 3–4 | 1 (2.4) | 24 (21.1) | 0.005 |
CLDa | 34 (81.0) | 71 (62.8) | 0.032 |
Weight at Discharge z-score | −1.8 ± 1.1 | −2.8 ± 1.2 | 0.000 |
Length at Discharge z-score | −2.1 ± 1.2 | −3.6 ± 1.4 | 0.000 |
Head circumference at Discharge z-score | −0.8 ± 1.5 | −2.0 ± 1.0 | 0.000 |
Death or GDD | 37 (77.1) | 89 (72.4) | 0.53 |
CP | 1 (2.4) | 10 (9.0) | 0.16 |
Abnormal hearing test at discharge | 1 (2.4) | 8 (7.1) | 0.26 |
Hearing loss requiring hearing aids or implants | 0 (0.0) | 7 (6.3) | 0.10 |
Isolated speech delay | 2 (4.8) | 19 (17.1) | 0.047 |