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Table 1 Characteristics of the included studies

From: Stapled versus hand-sewn intestinal anastomosis in pediatric patients: a systematic review and meta-analysis

References Author name and year of publication

Country

Study Type

Sample

size

Follow-up period

Etiology

Age (days)

Body weight (kg)

   

SA

HA

 

SA

HA

SA

HA

Wrighton 2008 [5]

USA

R

106

189

up to 9 years

Small intestinal atresia

NEC

FIP

Anorectal malformation with colostomy closure

Bowel obstruction

Colonic stricture or atresia

Bowel perforation

Intussusception

105.7

44.5

5.17

3.13

Kozlov

2012 [6]

Russia

R

21

23

averaged 6 months

NEC and FIP

Patent omphalomesenteric duct

Bowel obstruction

Anorectal malformation

Gastroschisis

Intestinal duplication

Hirschsprung disease

23.2

19.7

2.72

2.88

Muncie

2017 [7]

USA

R

38

33

3 months

NEC

Small intestinal atresia

FIP

Gastroschisis

Volvulus

Bowel ischemia after colostomy

Intussusception

Perforated small bowel

obstruction

Anastomotic stricture

≤ 60days

(20 %)

61-120days

(74 %)

> 120days

(67 %)

≤ 60days

(80 %)

61-120days

(26 %)

> 120days

(33 %)

2.52

2.15

Hintz

2018 [8]

Canada

R

23

67

median of approximately 1 year

Anorectal malformation

Intestinal atresia

Hirschsprung disease

Volvulus

Intussusception

Meconium ileus

Small bowel obstruction

Intestinal duplication

Gastroschisis

Meckel’s diverticulum

NEC

FIP

Dysmotility

Familial intrahepatic cholestasis

Foreign body ingestion

Internal hernia

Intestinal stenosis

Trauma

10.5

months

8.9

months

8.2

7.95

Amano

2018 [9]

Japan

R

13

64

-

Small intestinal atresia

Stoma

Meconium peritonitis

Volvulus

Intestinal duplication

Meckel’s diverticulum

Intestinal perforation

Ileus

2

3

2.8

2.6

Mitra

2020 [10]

India

RCT

28

28

-

Small intestinal atresia

Duodenal atresia

Intussusception

Patent vitellointestinal duct

Meckel’s diverticulum

Ileostomy closure

Total colonic aganglionosis

Hirschsprung disease

Ileal perforation

Gastroschisis

Obstructed umbilical hernia

8.89

months

8.39

months

4.11

3.85

  1. SA stapled anastomosis, HA hand-sewn anastomosis, R retrospective cohort study, RCT randomized controlled trial, NEC necrotizing enterocolitis, FIP focal intestinal perforation