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Table 1 Characteristics of the included studies

From: Stapled versus hand-sewn intestinal anastomosis in pediatric patients: a systematic review and meta-analysis

References Author name and year of publication Country Study Type Sample
size
Follow-up period Etiology Age (days) Body weight (kg)
    SA HA   SA HA SA HA
Wrighton 2008 [5] USA R 106 189 up to 9 years Small intestinal atresia
NEC
FIP
Anorectal malformation with colostomy closure
Bowel obstruction
Colonic stricture or atresia
Bowel perforation
Intussusception
105.7 44.5 5.17 3.13
Kozlov
2012 [6]
Russia R 21 23 averaged 6 months NEC and FIP
Patent omphalomesenteric duct
Bowel obstruction
Anorectal malformation
Gastroschisis
Intestinal duplication
Hirschsprung disease
23.2 19.7 2.72 2.88
Muncie
2017 [7]
USA R 38 33 3 months NEC
Small intestinal atresia
FIP
Gastroschisis
Volvulus
Bowel ischemia after colostomy
Intussusception
Perforated small bowel
obstruction
Anastomotic stricture
≤ 60days
(20 %)
61-120days
(74 %)
> 120days
(67 %)
≤ 60days
(80 %)
61-120days
(26 %)
> 120days
(33 %)
2.52 2.15
Hintz
2018 [8]
Canada R 23 67 median of approximately 1 year Anorectal malformation
Intestinal atresia
Hirschsprung disease
Volvulus
Intussusception
Meconium ileus
Small bowel obstruction
Intestinal duplication
Gastroschisis
Meckel’s diverticulum
NEC
FIP
Dysmotility
Familial intrahepatic cholestasis
Foreign body ingestion
Internal hernia
Intestinal stenosis
Trauma
10.5
months
8.9
months
8.2 7.95
Amano
2018 [9]
Japan R 13 64 - Small intestinal atresia
Stoma
Meconium peritonitis
Volvulus
Intestinal duplication
Meckel’s diverticulum
Intestinal perforation
Ileus
2 3 2.8 2.6
Mitra
2020 [10]
India RCT 28 28 - Small intestinal atresia
Duodenal atresia
Intussusception
Patent vitellointestinal duct
Meckel’s diverticulum
Ileostomy closure
Total colonic aganglionosis
Hirschsprung disease
Ileal perforation
Gastroschisis
Obstructed umbilical hernia
8.89
months
8.39
months
4.11 3.85
  1. SA stapled anastomosis, HA hand-sewn anastomosis, R retrospective cohort study, RCT randomized controlled trial, NEC necrotizing enterocolitis, FIP focal intestinal perforation