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Table 3 Univariate and multivariate logistic regression analysis evaluated risk factors predicting hypovitaminosis D

From: Hypovitaminosis D and risk factors in pediatric epilepsy children

Factor Univariate model Multivariate model
Crude
Odds Ratio
95%CI p-value Adjusted
Odds Ratio
95%CI p-value
Gender
  male 1    1   
  female 1.935 0.904-4.14 0.089 1.568 0.649-3.786 0.318
Puberty status
  prepuberty 1    1   
  puberty 4.911 1.983-12.159 0.001* 5.426 1.879-15.67 0.002*
Duration of sun exposed, during 10 am-14 pm
  <  60 min/day 3.357 0.852-13.223 0.083 2.68 0.455-15.79 0.276
  ≥ 60 min/day 1    1   
Monotherapy
  No 1    1   
  Yes 1.628 0.772-3.434 0.201 1.49 0.442-5.028 0.520
Enzyme-inducer ASMs (CBZ,PB,PHT)
  No 1    1   
  Yes 1.453 0.536-3.939 0.463 1.306 0.372-4.582 0.677
Enzyme-inhibitor ASMs (VPA)
  No 1.97 0.932-4.162 0.074 3.578 1.117-11.46 0.032*
  Yes 1    1   
BZD and Newer ASMs
  No 1.363 0.500-3.712 0.545 2.029 0.376-10.941 0.411
  Yes 1    1   
Duration of ASMs used
  ≤ 2 years 1    1   
  >  2 years 2.667 1.175-6.05 0.019* 2.222 0.827-5.969 0.113
  1. ASMs anti-seizure medications; CBZ Carbamazepine; PB Phenobarbital; PHT Phenytoin; VPA Valproate; BZD Benzodiazepine
  2. *p-value significant at < 0.05