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Table 1 Differences in feeding protocols between cohorts

From: Enteral feeding advancement and growth until 5 years in extremely preterm infants

 

Cohort 1

Cohort 2

Start of enteral feeds within 4 h of birth

10–15 ml/kg/d

20 ml/kg/d

Increase in daily enteral feeding volume

15–20 ml/kg/day

25–30 ml/kg/day

Cut-off for of gastric residual volume considered “normal”

(in infants with unremarkable abdominal clinical status)

1–2 ml/kg

< 4 ml/kg

Start of breast milk fortification (FM85, Nestle, Frankfurt) at enteral feeding intake

≥150 ml/kg/d

≥100 ml/kg/d

Parenteral protein administration (day1)

2.5 g/kg/day

3.0 g/kg/d