Table 2 Comparative analysis of the characteristics of 117 patients with West syndrome according to treatment group

Number

78

39

Male sex, n (%)

42 (53.8)

20 (51.3)

0.799

Socioeconomic position

n = 64

n = 25

     Cluster

6.0 ± 2.4

5.9 ± 2.3

0.909

     Index

0.447 ± 1.086

0.406 ± 1.031

0.871

Residency status, n (%)

     Israeli

65 (83.3)

26 (66.7)

0.043

     Tourists

13 (16.7)

13 (33.3)

Gestational age

n = 66

n = 19

     Gestational age, weeks

39 (36–40)

39.5 (28–41)

0.560

    Preterm < 37 weeks’ gestation, n (%)

17 (25.8)

8 (42.1)

0.050

     Term 38–42 weeks’ gestation, n (%)

46 (69.7)

8 (42.1)

     Postterm > 42 weeks gestation, n (%)

3 (4.5)

3 (15.8)

Birth parameters

     Birth weight, z-score

-0.34 ± 0.94

-0.27 ± 1.02

0.787

     Head circumference, z-score

-0.45 ± 0.47

-1.37 ± 0.40

0.005

West syndrome

     Age at diagnosis, months

5.9 ± 3.0

7.5 ± 4.2

0.031

Etiology, n (%)

n = 78

n = 39

     Unknown, normal development

12 (15.4)

8 (20.5)

0.991

     Unknown, developmental delay

13 (16.7)

6 (15.4)

     Genetic syndrome

18 (23.1)

9 (23.1)

     Structural, congenital

6 (7.7)

2 (5.1)

     Structural, acquired

29 (37.2)

14 (35.9)

     Metabolic

0 (0)

0 (0)

Brain imaging - MRI/CT, n (%)

n = 72

n = 31

     Normal

14 (19.4)

5 (16.1)

0.693

     Pathologic

58 (80.6)

26 (83.9)

Cerebral palsy, n (%)

26 (33.3)

13 (33.3)

1

Psychomotor development, n (%)

n = 69

n = 29

     Normal

10 (14.5)

0 (0)

0.040

     Mild developmental delay

9 (13)

2 (6.9)

     Moderate developmental delay

21 (30.4)

16 (55.2)

     Severe developmental delay

29 (42)

11 (37.9)