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Table 2 Univariate comparison of patients not hospitalized vs. hospitalized among symptomatic SARS-CoV-2 positive children and adolescents diagnosed between 3/12/2020 and 9/28/2020

From: The first 1000 symptomatic pediatric SARS-CoV-2 infections in an integrated health care system: a prospective cohort study

  Not hospitalized (n = 959) Hospitalized (n = 41) OR (95 % CI) p-value
Age, mean ± SD, median (IQR) 12.1 ± 6.0, 14.1 (7.4–17.3) 10.0 ± 7.7, 12.2 (0.9–17.1) 0.95 (0.90-1.00) 0.077b
Male gender 459 (47.9 %) 18 (43.9 %) 0.9 (0.5–1.6) 0.619a
Race     0.086a
 White 760 (79.2 %) 29 (70.7 %) Reference  
 Black 118 (12.3 %) 10 (24.4 %) 2.2 (1.1–4.7)  
 Asian 41 (4.3 %) 2 (4.9 %) 1.3 (0.3–5.5)  
 Other 40 (4.2 %) 0 (0.0 %) 0.0 (0.0-∞)  
 Hispanic 188 (19.6 %) 15 (36.6 %) 2.4 (1.2–4.6) 0.008a
 Black or Hispanic 304 (31.7 %) 25 (61.0 %) 3.4 (1.8–6.4) < 0.001a
Body mass index, mean ± SD, median, BMI Category 21.9 ± 5.5, 21.0 (18.0-24.4) 22.5 ± 7.7, 20.9 (16.1–25.6) 1.02 (0.96–1.08) 0.849b
0.435a
 Underweight 153 (28.4 %) 12 (35.3 %) 1.49 (0.67–3.3)  
 Normal weight  266 (49.4 %) 14 (41.2 %) Reference  
 Overweight 72 (13.4 %) 3 (8.8 %) 0.79 (0.22–2.83)  
 Obese 47 (8.7 %) 5 (14.7 %) 2.02 (0.70–5.88)  
Clinical Symptoms     0.229a
 Anosmia (loss of smell) 162 (16.9 %) 4 (9.8 %) 0.5 (0.2–1.5)  
 Shortness of breath(dyspnea) 81 (8.4 %) 17 (41.5 %) 7.7 (4.0-14.9) < 0.001a
 Sore throat 357 (37.2 %) 4 (9.8 %) 0.2 (0.1–0.5) < 0.001a
 Vomiting 12 (1.3 %) 4 (9.8 %) 8.5 (2.6–27.7) < 0.001a
 Fever > 100.4 F 314 (32.7 %) 23 (56.1 %) 2.6 (1.4–4.9) 0.002a
 Headache 420 (43.8 %) 4 (9.8 %) 0.2 (0.05–0.39) < 0.001a
 Hypoxia 1 (0.1 %) 11 (26.8 %) 351.3 (43.9-2809.2) < 0.001a
 Abdominal pain 74 (7.7 %) 8 (19.5 %) 2.9 (1.3–6.5) 0.007a
 Nausea or vomiting 139 (14.5 %) 8 (19.5 %) 1.4 (0.6–3.2) 0.374 a
Pre-existing condition(s) 150 (15.6 %) 27 (65.9 %) 10.4 (5.3–20.3) < 0.001a
 Immunocompromising condition 4 (0.4 %) 5 (12.2 %) 33.2 (8.5-128.7) < 0.001a
 Neurologic condition 24 (2.5 %) 9 (22.0 %) 11.0 (4.7–25.5) < 0.001a
 Cardiovascular disease 19 (2.0 %) 8 (19.5 %) 12.0 (4.9–29.4) < 0.001a
 Chronic renal disease 5 (0.5 %) 3 (7.3 %) 15.1 (3.5–65.4) < 0.001a
 Chronic lung disease 69 (7.2 %) 8 (19.5 %) 3.1 (1.4-7.0) < 0.004a
 Diabetes 9 (0.9 %) 1 (2.4 %) 2.6 (0.3–21.3) < 0.344a
 Other chronic condition 53 (5.5 %) 11 (26.8 %) 6.3 (3.0-13.2) < 0.001a
  1. adenotes a P value based on a chi-square test
  2. bdenotes a P value based a Mann-Whitney U test
  3. cdenotes a P value based on a Fisher’s exact test