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Table 2 Comparison between Subjects with Mild or no Fibrosis (F≤1) and Subjects with Moderate/Severe Fibrosis (F≥2)

From: Higher BMI predicts liver fibrosis among obese children and adolescents with NAFLD - an interventional pilot study

  Fibrosis ≤1
n = 33
Fibrosis ≥2
n = 24
P Value
Age, year 12.9±2.8 14.3±2.8 0.058
Male (%) 22 (66) 13 (54) NS
Birth weight (kg) 2.9±6.5 2.9±8 NS
Breastfeeding (%) 11 (34) 6 (26) NS
High SES (%) 13 (41.7) 9 (41.9) NS
Age at adiposity rebound 6.7±2.8 5.2±2.7 NS
BMI 34.9±8 43.8±9.5 <0.001
BMI Z score 2.4±0.3 2.8±0.6 0.004
Triglycerides, mg/dL 133±61 112.9±49 NS
LDL, mg/dL 116.7±38.2 92.4±29.3 0.04
HDL, mg/dL 40.9±10.3 42.1±12.2 NS
HbA1c 5.3±0.3 5.4±0.5 NS
OSA (%) 2(4) 3(19) NS
ALT, U/L 39.3±29.8 52.8±44.4 NS
Moderate/severe steatosis, n (%) 10 (32) 21 (67) <0.01
HRI 1.8±0.5 2.1±0.4 0.02
  1. Values are expressed as mean and standard deviation (SD) or %
  2. BMI body mass index; ALT alanine transaminase; LDL low-density lipoprotein; HDL high-density lipoprotein, HRI hepatorenal index; SES socioeconomic status; OSA Obstructive sleep apnea