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Table 2 Comparison between Subjects with Mild or no Fibrosis (F≤1) and Subjects with Moderate/Severe Fibrosis (F≥2)

From: Higher BMI predicts liver fibrosis among obese children and adolescents with NAFLD - an interventional pilot study

 

Fibrosis ≤1

n = 33

Fibrosis ≥2

n = 24

P Value

Age, year

12.9±2.8

14.3±2.8

0.058

Male (%)

22 (66)

13 (54)

NS

Birth weight (kg)

2.9±6.5

2.9±8

NS

Breastfeeding (%)

11 (34)

6 (26)

NS

High SES (%)

13 (41.7)

9 (41.9)

NS

Age at adiposity rebound

6.7±2.8

5.2±2.7

NS

BMI

34.9±8

43.8±9.5

<0.001

BMI Z score

2.4±0.3

2.8±0.6

0.004

Triglycerides, mg/dL

133±61

112.9±49

NS

LDL, mg/dL

116.7±38.2

92.4±29.3

0.04

HDL, mg/dL

40.9±10.3

42.1±12.2

NS

HbA1c

5.3±0.3

5.4±0.5

NS

OSA (%)

2(4)

3(19)

NS

ALT, U/L

39.3±29.8

52.8±44.4

NS

Moderate/severe steatosis, n (%)

10 (32)

21 (67)

<0.01

HRI

1.8±0.5

2.1±0.4

0.02

  1. Values are expressed as mean and standard deviation (SD) or %
  2. BMI body mass index; ALT alanine transaminase; LDL low-density lipoprotein; HDL high-density lipoprotein, HRI hepatorenal index; SES socioeconomic status; OSA Obstructive sleep apnea