From: The factors associated with transient hypothyroxinemia of prematurity
Risk factors | THOP group | Control group | P value |
---|---|---|---|
Participants, (n) | 71 | 73 | Â |
BW (g) | 1306,52 ± 446 | 1544,93 ± 498 | < 0.001 |
Apgar score < 7 (5th minute) | 34 (48) | 24 (33) | 0.066 |
Apgar score ≥ 7 (5th minute) | 37 (52) | 49 (67) |  |
Delivery type (C/S) | 63 (89) | 67 (92) | 0.537 |
FGR | 19 (27) | 12 (16) | 0.132 |
SGA | 15 (21) | 4 (5) | 0.006 |
PRENATAL | |||
 Maternal smoking | 5 (7) | 5 (7) | 1.000 |
 IVF | 8 (11) | 7 (10) | 0.955 |
 GDM | 6 (9) | 13 (18) | 0.097 |
 Gestational hypertension | 20 (28) | 21 (29) | 1.000 |
 Prenatal betamethasone treatment | 47 (66) | 48 (66) | 1.000 |
MEDICINE | |||
 Vancomycin+amikacin | 9 (13) | 5 (7) | 0.238 |
 Ampicillin+gentamicin | 36 (51) | 41 (56) | 0.511 |
 Surfactant | 39 (55) | 34 (46) | 0.403 |
 Caffeine | 59 (83) | 57 (78) | 0.582 |
 Dobutamine | 8 (11) | 3 (4) | 0.106 |
 Dopamine | 17 (24) | 13 (18) | 0.365 |
 Midazolam | 23 (32) | 21 (29) | 0.637 |
 Fentanyl | 4 (6) | 2 (3) | 0.385 |
 Paracetamol | 3 (4) | 2 (3) | 0.679 |
 Ibuprofen | 9 (13) | 4 (6) | 0,132 |
 Fluconazole prophylaxis | 34 (48) | 32 (44) | 0.626 |
CLINICAL-DIAGNOSIS | |||
 RDS | 39 (55) | 34 (56) | 0.403 |
 IVH | 24 (34) | 12 (16) | 0.022 |
 Pneumothorax | 3 (4) | 4 (5) | 0.726 |
 PDA | 12/59 (20)* | 6/57 (11)* | 0.144 |
 CHD | 15/59 (25)* | 5/57 (9)* | 0.018 |
 ROP | 3 (4) | 1 (1) | 0.448 |
 BPD | 26 (37) | 16 (22) | 0.052 |
 Hypoglycemia | 21 (30) | 23 (31) | 0.802 |
 Sepsis | 7 (10) | 9 (12) | 0.837 |
TRANSFUSIONS | |||
 ES transfusion | 18 (25) | 13 (18) | 0.271 |
 TS transfusion | 5 (7) | 5 (7) | 0.964 |
 FFP transfusion | 23 (32) | 19 (26) | 0.401 |
CLINICAL APPLICATIONS | |||
 Phototherapy | 66 (93) | 68 (93) | 0.964 |
 Central catheter | 57 (80) | 57 (78) | 0.905 |
 Ventilator support | 31 (43) | 28 (38) | 0.517 |
 NIV support | 48 (68) | 54 (74) | 0.511 |